Close
Help





JOURNAL

Bioinformatics and Biology Insights

A Plausible Role for the Presence of Internal Shine-Dalgarno Sites

Submit a Paper


Bioinformatics and Biology Insights 2010:4 55-60

Original Research

Published on 28 Jun 2010

DOI: 10.4137/BBI.S5236


Further metadata provided in PDF



Sign up for email alerts to receive notifications of new articles published in Bioinformatics and Biology Insights

Abstract

The presence of nucleotide hybridization between the 3′ end of 16S rRNA and mRNA sequence upstream of the start codon is well known in bacteria. In this paper, we detect the presence of such hybridization sites inside the coding regions of E. coli genes, and analyze their proximity to clusters of slow-translating codons. We study this phenomenon in genes of high and low expression separately. Based on our findings, we propose an explanation for the presence of RNA hybridization within the translated regions of bacterial genes.



Downloads

PDF  (491.68 KB PDF FORMAT)

RIS citation   (ENDNOTE, REFERENCE MANAGER, PROCITE, REFWORKS)

BibTex citation   (BIBDESK, LATEX)

XML





Quick Links


New article and journal news notification services