Close
Help




JOURNAL

Breast Cancer: Basic and Clinical Research

Advanced MRI Techniques in the Evaluation of Complex Cystic Breast Lesions

Submit a Paper


Breast Cancer: Basic and Clinical Research 2016:10 71-76

Original Research

Published on 09 Jun 2016

DOI: 10.4137/BCBCR.S38535


Further metadata provided in PDF



Sign up for email alerts to receive notifications of new articles published in Breast Cancer: Basic and Clinical Research

Abstract

Objective: The purpose of this research work was to evaluate complex cystic breast lesions by advanced MRI techniques and correlating imaging with histologic findings.

Methods and materials: In a cross-sectional design from September 2013 to August 2015, 50 patients having sonographically detected complex cystic lesions of the breast were included in the study. Morphological characteristics were assessed. Dynamic contrast-enhanced MRI along with diffusion-weighted imaging and MR spectroscopy were used to further classify lesions into benign and malignant categories. All the findings were correlated with histopathology.

Results: Of the 50 complex cystic lesions, 32 proved to be benign and 18 were malignant on histopathology. MRI features of heterogeneous enhancement on CE-MRI (13/18), Type III kinetic curve (13/18), reduced apparent diffusion coefficient (18/18), and tall choline peak (17/18) were strong predictors of malignancy. Thirteen of the 18 lesions showed a combination of Type III curve, reduced apparent diffusion coefficient value, and tall choline peak.

Conclusions: Advanced MRI techniques like dynamic imaging, diffusion-weighted sequences, and MR spectroscopy provide a high level of diagnostic confidence in the characterization of complex cystic breast lesion, thus allowing early diagnosis and significantly reducing patient morbidity and mortality. From our study, lesions showing heterogeneous contrast enhancement, Type III kinetic curve, diffusion restriction, and tall choline peak were significantly associated with malignant complex cystic lesions of the breast.



Downloads

PDF  (2.12 MB PDF FORMAT)

RIS citation   (ENDNOTE, REFERENCE MANAGER, PROCITE, REFWORKS)

BibTex citation   (BIBDESK, LATEX)

XML




What Your Colleagues Say About Breast Cancer: Basic and Clinical Research
I had a great experience publishing our paper in Breast Cancer: Basic and Clinical Research. The editorial team is very friendly and helpful. I was updated frequently during the entire review and publishing process. The review process is very reasonable and fair. The editor in charge has good judgement on review comments. I would recommend this journal to any researchers who conduct breast cancer research.
Dr Yanfen Hu (University of Texas Health Science Center at San Antonio, San Antonio, TX, USA)
More Testimonials

Quick Links


New article and journal news notification services