Sign up for email alerts to receive notifications of new articles published in Bioinformatics and Biology Insights
Proteins may be related to each other very specifically as homologous subfamilies. Proteins can also be related to diverse proteins at the super family level. It has become highly important to characterize the existing sequence databases by their signatures to facilitate the function annotation of newly added sequences. The algorithm described here uses a scheme for the classification of odorant binding proteins on the basis of functional residues and Cys-pairing. The cysteine-based scoring scheme not only helps in unambiguously identifying families like odorant binding proteins (OBPs), but also aids in their classification at the subfamily level with reliable accuracy. The algorithm was also applied to yet another cysteine-rich family, where similar accuracy was observed that ensures the application of the protocol to other families.
PDF (7.42 MB PDF FORMAT)
RIS citation (ENDNOTE, REFERENCE MANAGER, PROCITE, REFWORKS)
BibTex citation (BIBDESK, LATEX)
We found Bioinformatics and Biology insights very supportive and quick in guiding us in submitting our manuscript. The review of the manuscript was also very prompt. We also found that the review was fair and prompt and that was the most important thing for us. It was a very interesting experience for us. We also liked the video abstract service, which is very novel and encouraging for authors.