Sign up for email alerts to receive notifications of new articles published in Clinical Medicine Insights: Blood Disorders
To assess some simple blood parameters at birth that can be used as a basis to suspect α-thalassemia minor (ATM), a prospective study involving 202 consecutive neonates with MCV of less than 95 ﬂ or less were checked for Hb Barts by HPLC. The group was divided into two, one with an MCV of 90–95 (89 cases) and the other with an MCV below 90 (113 cases). For control, 104 consecutive neonates with an MCV 95 ﬂ were similarly checked. It has been confirmed that an MCV that is below 90 ﬂ, especially with and MCH of 30 pg is a strong indicator of the presence of ATM (109/113). On the other hand, MCV of 90 or more, especially with an MCH of 30 or more is a strong negative indicator for ATM (70/89). Firm diagnosis of ATM at birth can thus be secured in majority of neonates.
PDF (203.23 KB PDF FORMAT)
RIS citation (ENDNOTE, REFERENCE MANAGER, PROCITE, REFWORKS)
BibTex citation (BIBDESK, LATEX)
The submission process for publication in Clinical Medicine Insights: Case Reports is extremely smooth. The editors were very fast in their response and provided detailed instructions about all procedures. They were happy to answer to all our questions. The whole process was fast and efficient.