Results 1-50 of 247 for Genomics

Multiple Testing in the Context of Gene Discovery in Sickle Cell Disease Using Genome-Wide Association Studies
Kevin H.M. Kuo
Genomics Insights 2017:10 1178631017721178
Review | Published on 01 Aug 2017

Consistency and Variability of DNA Methylation in Women During Puberty, Young Adulthood, and Pregnancy
Su Chen, Nandini Mukherjee, Vimala Devi Janjanam, S Hasan Arshad, Ramesh J Kurukulaaratchy, John W Holloway, Hongmei Zhang, Wilfried Karmaus
Genetics & Epigenetics 2017:9 1179237X17721540
Original Research | Published on 28 Jul 2017

Linear-In-Flux-Expressions Methodology: Toward a Robust Mathematical Framework for Quantitative Systems Pharmacology Simulators
Sean T McQuade, Ruth E Abrams, Jeffrey S Barrett, Benedetto Piccoli, Karim Azer
Gene Regulation and Systems Biology 2017:11 1177625017711414
Review | Published on 26 Jul 2017

Insights Into Signaling in Cell-Based Therapy for Heart Disease
Angela C Rieger, Bryon A Tompkins, Monisha Banerjee, Makoto Natsumeda, Victoria Florea, Ivonne H Schulman
Signal Transduction Insights 2017:6 1178643417717688
Review | Published on 10 Jul 2017

A Quantitative Systems Pharmacology Platform to Investigate the Impact of Alirocumab and Cholesterol-Lowering Therapies on Lipid Profiles and Plaque Characteristics
Jeffrey E Ming, Ruth E Abrams, Derek W Bartlett, Mengdi Tao, Tu Nguyen, Howard Surks, Katherine Kudrycki, Ananth Kadambi, Christina M Friedrich, Nassim Djebli, Britta Goebel, Alex Koszycki, Meera Varshnaya, Joseph Elassal, Poulabi Banerjee, William J Sasiela, Michael J Reed, Jeffrey S Barrett, Karim Azer
Gene Regulation and Systems Biology 2017:11 1177625017710941
Original Research | Published on 22 Jun 2017

A Transcriptional Regulatory Role for the Membrane Type-1 Matrix Metalloproteinase in Carcinogen-Induced Inflammasome Gene Expression
Samuel Sheehy, Borhane Annabi
Gene Regulation and Systems Biology 2017:11 1177625017713996
Original Research | Published on 08 Jun 2017

Overexpression and Knockdown of Hypoxia-Inducible Factor 1 Disrupt the Expression of Steroidogenic Enzyme Genes and Early Embryonic Development in Zebrafish
Tianfeng Tan, Richard Man Kit Yu, Rudolf Shiu Sun Wu, Richard Yuen Chong Kong
Gene Regulation and Systems Biology 2017:11 1177625017713193
Original Research | Published on 08 Jun 2017

Mechanistic Modelling of Drug-Induced Liver Injury: Investigating the Role of Innate Immune Responses
Lisl KM Shoda, Christina Battista, Scott Q Siler, David S Pisetsky, Paul B Watkins, Brett A Howell
Gene Regulation and Systems Biology 2017:11 1177625017696074
Review | Published on 30 May 2017

Effects of High-Fat Feeding on Skeletal Muscle Gene Expression in Diabetic Goto-Kakizaki Rats
Jing Nie, Debra C DuBois, Bai Xue, William J Jusko, Richard R Almon
Gene Regulation and Systems Biology 2017:11 1177625017710009
Original Research | Published on 29 May 2017

The Synergistic Role of Light-Feeding Phase Relations on Entraining Robust Circadian Rhythms in the Periphery
Seul-A Bae, Ioannis P Androulakis
Gene Regulation and Systems Biology 2017:11 1177625017702393
Review | Published on 20 Apr 2017

Time Course Expression Analysis of 1[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole Induction of Cytoprotection in Human Endothelial Cells
James A Bynum, Xinyu Wang, Salomon A Stavchansky, Phillip D Bowman
Gene Regulation and Systems Biology 2017:11 1177625017701106
Original Research | Published on 07 Apr 2017

Use of Biomedical Ontologies for Integration of Biological Knowledge for Learning and Prediction of Adverse Drug Reactions
Shadia Zaman, Sirarat Sarntivijai, Darrell R Abernethy
Gene Regulation and Systems Biology 2017:11 1177625017696075
Review | Published on 15 Mar 2017

Graphical Modeling Meets Systems Pharmacology
Rosario Lombardo, Corrado Priami
Gene Regulation and Systems Biology 2017:11 1177625017691937
Perspective | Published on 10 Mar 2017

Identifying Cell Type-Specific Transcription Factors by Integrating ChIP-seq and eQTL Data–Application to Monocyte Gene Regulation
Mudra Choudhury and Stephen A. Ramsey
Gene Regulation and Systems Biology 2016:10 105-110
Methodology | Published on 13 Dec 2016

DNA Methylation of Regulatory Regions of Imprinted Genes at Birth and Its Relation to Infant Temperament
Bernard F. Fuemmeler, Chien-Ti Lee, Adelheid Soubry, Edwin S. Iversen, Zhiqing Huang, Amy P. Murtha, Joellen M. Schildkraut, Randy L. Jirtle, Susan K. Murphy and Cathrine Hoyo
Genetics & Epigenetics 2016:8 59-67
Original Research | Published on 28 Nov 2016

A Comparison of Genome-wide and Exome-wide Somatic Mutation Patterns in Tumors
Emily Mulhern, Robert Vaughn, Mikaela Vega, Edward Abel, Astrid Cerrato, Yashwan Kalainesan, Roxanne Hinch, Sarangan Ravichandran and Brian T. Luke
Journal of Genomes and Exomes 2016:5 9-16
Original Research | Published on 22 Nov 2016

DNA Methylation of Cellular Retinoic Acid-Binding Proteins in Cervical Cancer
Ana L. Arellano-Ortiz, Mauricio Salcedo-Vargas, Claudia L. Vargas-Requena, José A. López-Díaz, Antonio De la Mora-Covarrubias, Juan C. Silva-Espinoza and Florinda Jiménez-Vega
Genetics & Epigenetics 2016:8 53-57
Original Research | Published on 10 Nov 2016

Semi-Automated Curation Allows Causal Network Model Building for the Quantification of Age-Dependent Plaque Progression in ApoE⁻/⁻ Mouse
Justyna Szostak, Florian Martin, Marja Talikka, Manuel C. Peitsch and Julia Hoeng
Gene Regulation and Systems Biology 2016:10 95-103
Original Research | Published on 06 Nov 2016

Insights on Diversity of Leucine-Rich Repeat (LRR) Domain among Major Blast Resistance Genes of Rice
S.J.S. Rama Devi, B. Umakanth, B. Vishalakshi, Supriya B. Aglawe, V. Ravindra Babu and Maganti S. Madhav
Journal of Genomes and Exomes 2016:5 1-7
Original Research | Published on 20 Oct 2016

SNP Marker Discovery in Pima Cotton (Gossypium barbadense L.) Leaf Transcriptomes
Pratibha Kottapalli, Mauricio Ulloa, Kameswara Rao Kottapalli, Paxton Payton and John Burke
Genomics Insights 2016:9 51-60
Original Research | Published on 02 Oct 2016

Epigenetics and Cellular Metabolism
Wenyi Xu, Fengzhong Wang, Zhongsheng Yu and Fengjiao Xin
Genetics & Epigenetics 2016:8 43-51
Review | Published on 25 Sep 2016

Novel Approach to Analyzing MFE of Noncoding RNA Sequences
Tina P. George and Tessamma Thomas
Genomics Insights 2016:9 41-49
Original Research | Published on 18 Sep 2016

Integrated Stress Response Signaling Pathways Induced by Supraphysiological Concentrations of Thyroid Hormone Inhibit Viral Replication
Mohammad Ishaq and Ven Natarajan
Signal Transduction Insights 2016:5 25-37
Original Research | Published on 30 Aug 2016

Dysregulation of Protein Kinase Gene Expression in NK Cells from Chronic Fatigue Syndrome/Myalgic Encephalomyelitis Patients
Anu Chacko, Donald R. Staines, Samantha C. Johnston and Sonya M. Marshall-Gradisnik
Gene Regulation and Systems Biology 2016:10 85-93
Original Research | Published on 28 Aug 2016

Provirus Silencing in Stem Cells: The Forbidden Regulators of Cell Fate
Sandeep Satapathy
Signal Transduction Insights 2016:5 15-23
Review | Published on 21 Aug 2016

DNA Microarray Highlights Nrf2-Mediated Neuron Protection Targeted by Wasabi-Derived Isothiocyanates in IMR-32 Cells
Phoebe Zapanta Trio, Satoru Fujisaki, Shunsuke Tanigawa, Ayami Hisanaga, Kozue Sakao, and De-Xing Hou
Gene Regulation and Systems Biology 2016:10 73-83
Original Research | Published on 11 Aug 2016

Resetting Human Naïve Pluripotency
Jifang Xiao, Daniel H. Mai and Liangqi Xie
Genetics & Epigenetics 2016:8 37-41
Review | Published on 04 Aug 2016

The Evolution of Epigenetics: From Prokaryotes to Humans and Its Biological Consequences
Amber Willbanks, Meghan Leary, Molly Greenshields, Camila Tyminski, Sarah Heerboth, Karolina Lapinska, Kathryn Haskins and Sibaji Sarkar
Genetics & Epigenetics 2016:8 25-36
Review | Published on 03 Aug 2016 | Video abstract

Endothelial Nitric Oxide Synthase (–786T>C) and Endothelin-1 (5665G.T) Gene Polymorphisms as Vascular Dysfunction Risk Factors in Sickle Cell Anemia
Wendell Vilas-Boas, Camylla V. B. Figueiredo, Thassila N. Pitanga, Magda O. S. Carvalho, Rayra P. Santiago, Sânzio S. Santana, Caroline C. Guarda, Angela M. D. Zanette, Bruno A. V. Cerqueira, and Marilda S. Gonçalves
Gene Regulation and Systems Biology 2016:10 67-72
Original Research | Published on 28 Jul 2016

Assessing the Causality Factors in the Association between (Abdominal) Obesity and Physical Activity among the Newfoundland Population—A Mendelian Randomization Analysis
Frank Barning and Taraneh Abarin
Genetics & Epigenetics 2016:8 15-24
Original Research | Published on 24 Jul 2016

Community-Reviewed Biological Network Models for Toxicology and Drug Discovery Applications
The sbv IMPROVER project team and challenge best performers: Aishwarya Alex Namasivayam, Alejandro Ferreiro Morales, Ángela María Fajardo Lacave, Aravind Tallam, Borislav Simovic, David Garrido Alfaro, Dheeraj Reddy Bobbili, Florian Martin, Ganna Androsova, Irina Shvydchenko, Jennifer Park, Jorge Val Calvo, Julia Hoeng, Manuel C. Peitsch, Manuel González Vélez Racero, Maria Biryukov, Marja Talikka, Modesto Berraquero Pérez, Neha Rohatgi, Noberto Díaz-Díaz, Rajesh Mandarapu, Rubén Amián Ruiz, Sergey Davidyan, Shaman Narayanasamy, Stéphanie Boué, Svetlana Guryanova, Susana Martínez Arbas, Swapna Menon and Yang Xiang
Gene Regulation and Systems Biology 2016:10 51-66
Original Research | Published on 12 Jul 2016

Killer Cell Immunoglobulin-like Receptor Genotype and Haplotype Investigation of Natural Killer Cells from an Australian Population of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis Patients
T. K. Huth, E. W. Brenu, D. R. Staines, and S. M. Marshall-Gradisnik
Gene Regulation and Systems Biology 2016:10 43-49
Original Research | Published on 19 Jun 2016

Integration of Telomere Length Dynamics into Systems Biology Framework: A Review
Lilit Nersisyan
Gene Regulation and Systems Biology 2016:10 35-42
Review | Published on 16 Jun 2016

Nucleotide Interdependency in Transcription Factor Binding Sites in the Drosophila Genome
Jacqueline M. Dresch, Rowan G. Zellers, Daniel K. Bork, and Robert A. Drewell
Gene Regulation and Systems Biology 2016:10 21-33
Original Research | Published on 12 Jun 2016

A STAT6 Intronic Single-Nucleotide Polymorphism is Associated with Clinical Malaria in Ghanaian Children
Daniel Amoako-Sakyi, Selorme Adukpo, Kwadwo A. Kusi, Daniel Dodoo, Michael F. Ofori, George O. Adjei, Dominic E. Edoh, Richard H. Asmah, Charles Brown, Bright Adu, Dorcas Obiri-Yeboah, Godfred Futagbi, Sharif Buari Abubakari, Marita Troye-Blomberg, Bartholomew D. Akanmori, Bamenla Q. Goka, John Arko-Mensah and Ben A. Gyan
Genetics & Epigenetics 2016:8 7-14
Original Research | Published on 29 May 2016

NEAT1 is Required for Survival of Breast Cancer Cells Through FUS and miR-548
Hao Ke, Limin Zhao, Xu Feng, Haibo Xu, Li Zou, Qin Yang, Xiaosan Su, Lingtao Peng and Baowei Jiao
Gene Regulation and Systems Biology 2016:Suppl. 1 11-17
Original Research | Published on 27 Apr 2016

Current View of microRNA Processing
Shuai Jiang and Wei Yan
Signal Transduction Insights 2016:5 9-13
Review | Published on 03 Apr 2016

MicroRNAs Circulate in the Hemolymph of Drosophila and Accumulate Relative to Tissue microRNAs in an Age-Dependent Manner
Joseph M. Dhahbi, Hani Atamna, Rui Li, Amy Yamakawa, Noel Guerrero, Hanh T. Lam, Patricia Mote and Stephen R. Spindler
Genomics Insights 2016:9 29-39
Original Research | Published on 28 Mar 2016 | Video abstract

Inferring Orthologs: Open Questions and Perspectives
Fredj Tekaia
Genomics Insights 2016:9 17-28
Review | Published on 25 Feb 2016

Estrogen Receptor Alpha (ESR1) Single-Nucleotide Polymorphisms (SNPs) Affect Malignant Melanoma Susceptibility and Disease Course
Hanna Glatthaar, Judith Katto, Thomas Vogt and Ulrich Mahlknecht
Genetics & Epigenetics 2016:8 1-6
Original Research | Published on 24 Feb 2016

Identification of Potential Anticancer Activities of Novel Ganoderma lucidum Extracts Using Gene Expression and Pathway Network Analysis
Chi H.J. Kao, Karen S. Bishop, Yuanye Xu, Dug Yeo Han, Pamela M. Murray, Gareth J. Marlow and Lynnette R. Ferguson
Genomics Insights 2016:9 1-16
Original Research | Published on 16 Feb 2016

Tamoxifen Action in ER-Negative Breast Cancer
Subrata Manna and Marina K. Holz
Signal Transduction Insights 2016:5 1-7
Review | Published on 10 Feb 2016

Expression and Presence of OPG and RANKL mRNA and Protein in Human Periodontal Ligament with Orthodontic Force
Liliana Otero, Dabeiba Adriana García and Liseth Wilches-Buitrago
Gene Regulation and Systems Biology 2016:10 15-20
Original Research | Published on 25 Jan 2016

Epigenetic Regulation of Tissue-Type Plasminogen Activator in Human Brain Tissue and Brain-Derived Cells
Martina Olsson, Karin Hultman, Sylvie Dunoyer-Geindre, Maurice A. Curtis, Richard L. M. Faull, Egbert K. O. Kruithof and Christina Jern
Gene Regulation and Systems Biology 2016:10 9-13
Rapid Communication | Published on 24 Jan 2016

Transcriptomic Sequencing Reveals a Set of Unique Genes Activated by Butyrate-Induced Histone Modification
Cong-Jun Li, Robert W. Li, Ransom L. Baldwin VI, Le Ann Blomberg, Sitao Wu and Weizhong Li
Gene Regulation and Systems Biology 2016:10 1-8
Original Research | Published on 21 Jan 2016

Biochemical Analysis of Genome Functions Using Locus-Specific Chromatin Immunoprecipitation Technologies
Toshitsugu Fujita and Hodaka Fujii
Gene Regulation and Systems Biology 2016:Suppl. 1 1-9
Review | Published on 18 Jan 2016

Alkaline Phosphatase-Positive Immortal Mouse Embryo Fibroblasts Are Cells in a Transitional Reprogramming State Induced to Face Environmental Stresses
Monica Evangelista, Mariama El Baroudi, Milena Rizzo, Andrea Tuccoli, Laura Poliseno, Marco Pellegrini and Giuseppe Rainaldi
Genetics & Epigenetics 2015:7 33-41
Original Research | Published on 28 Dec 2015

Aberrant Splicing of Estrogen Receptor, HER2, and CD44 Genes in Breast Cancer
Kazushi Inoue and Elizabeth A. Fry
Genetics & Epigenetics 2015:7 19-32
Review | Published on 02 Dec 2015

Applying Side-chain Flexibility in Motifs for Protein Docking
Hui Liu, Feng Lin, Jian-Li Yang, Hong-Rui Wang and Xiu-Ling Liu
Genomics Insights 2015:8 1-10
Original Research | Published on 15 Oct 2015

Csf2 and Ptgs2 Epigenetic Dysregulation in Diabetes-prone Bicongenic B6.NODC11bxC1tb Mice
Erin Garrigan, Nicole S. Belkin, Federica Seydel, Zhao Han, Jamal Carter, Marcia McDuffie, Laurence Morel, Ammon B. Peck, Michael J. Clare-Salzler, Mark Atkinson, Clive Wasserfall, Abdoreza Davoodi-Semiromi, Jing-da Shi, Carrie Haskell-Luevano, Li-Jun Yang, John J. Alexander, Autumn Cdebaca, Teresa Piliant, Corin Riggs, Matthew Amick and Sally A. Litherland
Genetics & Epigenetics 2015:7 5-17
Original Research | Published on 11 Oct 2015