Analytical Chemistry Insights

An international, peer-reviewed, open access journal focusing on analytical methodology, techniques, and instruments in the fundamental and applied areas of chemistry. Recognizing the close relationship between analytical chemistry and pharmaceutical analysis, the journal also seeks to address drug analysis, analytical methodology, and instrumentation. 

Editor in Chief: Professor Gabor Patonay

ISSN: 1177-3901

Processing Speed: High quality, constructive peer review and rapid editorial decision within an average of four weeks.

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Quality by Design–Applied Liquid Chromatography-Tandem Mass Spectrometry Determination of Enzalutamide Anti-Prostate Cancer Therapy Drug in Spiked Plasma Samples
ASK Sankar, Shanmugasundaram Palani, Ravichandiran Velayudham
Analytical Chemistry Insights 2017:12 1177390117726776
Original Research | Published on 28 Aug 2017

Comparison of 3 Derivatization Methods for the Analysis of Amphetamine-Related Drugs in Oral Fluid by Gas Chromatography-Mass Spectrometry
Khaled M Mohamed, Abdulsallam Bakdash
Analytical Chemistry Insights 2017:12 1177390117727533
Original Research | Published on 24 Aug 2017

Synthesis and Optical Properties of Pentamethine Cyanine Dyes With Carboxylic Acid Moieties
Tyler L Dost, Michael T Gressel, Maged Henary
Analytical Chemistry Insights 2017:12 1177390117711938
Original Research | Published on 30 May 2017

Review of Current Applications of Immunohistochemistry in Pediatric Nonneoplastic Gastrointestinal, Hepatobiliary, and Pancreatic Lesions
Joseph de Nanassy, Dina El Demellawy
Analytical Chemistry Insights 2017:12 1177390117690140
Review | Published on 18 Apr 2017

Colorimetric Detection Based on Localised Surface Plasmon Resonance Optical Characteristics for the Detection of Hydrogen Peroxide Using Acacia Gum–Stabilised Silver Nanoparticles
Eman Alzahrani
Analytical Chemistry Insights 2017:12 1177390116684686
Original Research | Published on 23 Feb 2017

Analytical Method Validation of High-Performance Liquid Chromatography and Stability-Indicating Study of Medroxyprogesterone Acetate Intravaginal Sponges
Nidal Batrawi, Shorouq Wahdan, Murad Abualhasan
Analytical Chemistry Insights 2017:12 1177390117690152
Original Research | Published on 20 Feb 2017

Insight into Biochemical Characterization of Plant Sesquiterpene Synthases
Tom Manczak and Henrik Toft Simonsen
Analytical Chemistry Insights 2016:Suppl. 1 1-7
Methodology | Published on 29 Sep 2016
This article is part of the special collection Bioanalytical chemistry

Development of Hollow-Fiber Liquid-Phase Microextraction Method for Determination of Urinary trans,trans-Muconic Acid as a Biomarker of Benzene Exposure
Farhad Ghamari, Abdulrahman Bahrami, Yadollah Yamini, Farshid Ghorbani Shahna and Abbas Moghimbeigi
Analytical Chemistry Insights 2016:11 65-71
Original Research | Published on 11 Sep 2016

Stability-Indicating High-Performance Liquid Chromatography Assay for the Determination of Sulthiame in Pharmaceutical Dosage Forms
Ammar Haidar, Sofiane Kabiche, Elyes Majoul, Issa-Bella Balde, Jean-Eudes Fontan, Salvatore Cisternino and Joël Schlatter
Analytical Chemistry Insights 2016:11 59-64
Original Research | Published on 06 Sep 2016

Extraction of Honey Polyphenols: Method Development and Evidence of Cis Isomerization
Thibaut Istasse, Nicolas Jacquet, Thomas Berchem, Eric Haubruge, Bach Kim Nguyen and Aurore Richel
Analytical Chemistry Insights 2016:11 49-57
Original Research | Published on 10 Aug 2016

On the Conflicting Estimations of Pigment Site Energies in Photosynthetic Complexes: A Case Study of the CP47 Complex
Tonu Reinot, Jinhai Chen, Adam Kell, Mahboobe Jassas, Kevin C. Robben, Valter Zazubovich and Ryszard Jankowiak
Analytical Chemistry Insights 2016:11 35-48
Expert Review | Published on 02 Jun 2016

Removal of 4-Nitrophenol from Water Using Ag-N-P-Tridoped TiO2 by Photocatalytic Oxidation Technique
Temesgen Achamo and O.P. Yadav
Analytical Chemistry Insights 2016:11 29-34
Original Research | Published on 04 Apr 2016

Quality Issues of Research Antibodies
Michael G. Weller
Analytical Chemistry Insights 2016:11 21-27
Review | Published on 20 Mar 2016

Development and Validation of Stability-Indicating RP-HPLC Method for Simultaneous Determination of Metformin HCl and Glimepiride in Fixed-Dose Combination
Pradnya N. Vaingankar and Purnima D. Amin
Analytical Chemistry Insights 2016:11 13-20
Original Research | Published on 13 Mar 2016

Electrochemical Behavior and Voltammetric Determination of a Manganese(II) Complex at a Carbon Paste Electrode
Sophia Karastogianni and Stella Girousi
Analytical Chemistry Insights 2016:11 1-11
Original Research | Published on 18 Jan 2016

Sample Preparation of Eggs From Laying Hens Using QuEChERS Dispersive Extraction for the Simultaneous Determination of Melamine and Cyromazine Residues by HPLC-DAD
Niki Tsartsali and Victoria F. Samanidou
Analytical Chemistry Insights 2015:10 53-58
Original Research | Published on 20 Dec 2015

A High-Performance Thin Layer Chromatography (HPTLC) Method for Simultaneous Determination of Diphenhydramine Hydrochloride and Naproxen Sodium in Tablets
R.P. Bhole, S.S. Shinde, S.S. Chitlange and S.B. Wankhede
Analytical Chemistry Insights 2015:10 47-51
Original Research | Published on 03 Dec 2015

Organ-on-a-Chip: New Platform for Biological Analysis
Fan An, Yueyang Qu, Xianming Liu, Runtao Zhong and Yong Luo
Analytical Chemistry Insights 2015:10 39-45
Review | Published on 29 Nov 2015

Spectrophotometric Investigations of Macrolide Antibiotics: A Brief Review
Mrudul R. Keskar and Ravin M. Jugade
Analytical Chemistry Insights 2015:10 29-37
Review | Published on 12 Nov 2015

Immunohistochemical Markers of Soft Tissue Tumors: Pathologic Diagnosis, Genetic Contributions, and Therapeutic Options
David M. Parham
Analytical Chemistry Insights 2015:Suppl. 1 1-10
Review | Published on 29 Oct 2015

Organophosphate Hydrolase in Conductometric Biosensor for the Detection of Organophosphate Pesticides
Ani Mulyasuryani and Sasangka Prasetyawan
Analytical Chemistry Insights 2015:10 23-27
Original Research | Published on 07 Oct 2015

Determination and Validation of a Solid-phase Extraction Gas Chromatography-mass Spectrometry for the Quantification of Methadone and Its Principal Metabolite in Human Plasma
Fouad Chiadmi and Joël Schlatter
Analytical Chemistry Insights 2015:10 17-22
Rapid Communication | Published on 26 Aug 2015

Spectrophotometric Determination of Cefixime Trihydrate in Pharmaceutical Formulations Based on Ion-Pair Reaction with Bromophenol Blue
Mrudul R. Keskar and Ravin M. Jugade
Analytical Chemistry Insights 2015:10 11-16
Original Research | Published on 27 Jul 2015

Determination of Chlorophenoxy Acid Methyl Esters and Other Chlorinated Herbicides by GC High-resolution QTOFMS and Soft lonization
Viorica Lopez-Avila, Patrick Roach and Randall Urdahl
Analytical Chemistry Insights 2015:10 1-9
Original Research | Published on 09 Feb 2015

A Study of Method Development, Validation, and Forced Degradation for Simultaneous Quantification of Paracetamol and Ibuprofen in Pharmaceutical Dosage Form by RP-HPLC Method
Md. Sarowar Jahan, Md. Jahirul Islam, Rehana Begum, Ruhul Kayesh and Asma Rahman
Analytical Chemistry Insights 2014:9 75-81
Methodology | Published on 18 Nov 2014

A Continuous Flow System for the Measurement of Ambient Nitrogen Oxides [NO + NO2] Using Rhodamine B Hydrazide as a Chemosensor
Pandurangappa Malingappa and Venkataramanappa Yarradoddappa
Analytical Chemistry Insights 2014:9 67-73
Original Research | Published on 17 Aug 2014

Preliminary Development of a Fiber Optic Sensor for Measuring Bilirubin
Steven M. Babin and Raymond M. Sova
Analytical Chemistry Insights 2014:9 59-65
Rapid Communication | Published on 01 Jul 2014

Corrigendum to “Utility of Experimental Design in Pre-Column Derivatization for the Analysis of Tobramycin by HPLC—Fluorescence Detection: Application to Ophthalmic Solution and Human Plasma”
Asmaa A. El-Zaher and Marianne A. Mahrouse
Analytical Chemistry Insights 2014:9 57-57
Corrigendum | Published on 11 Jun 2014

Determination of Xanthine in the Presence of Hypoxanthine by Adsorptive Stripping Voltammetry at the Mercury Film Electrode
Percio Augusto Mardini Farias and Arnaldo Aguiar Castro
Analytical Chemistry Insights 2014:9 49-55
Original Research | Published on 09 Jun 2014

Kinetic Study of the Alkaline Degradation of Oseltamivir Phosphate and Valacyclovir Hydrochloride using Validated Stability Indicating HPLC
Ramzia I. Al-Bagary, Asmaa A. El-Zaher, Fahima A. Morsy and Mai M. Fouad
Analytical Chemistry Insights 2014:9 41-48
Original Research | Published on 27 May 2014

Spectrophotometric and Spectrofluorimetric Studies on Azilsartan Medoxomil and Chlorthalidone to Be Utilized in Their Determination in Pharmaceuticals
Walid M. Ebeid, Ehab F. Elkady, Asmaa A. El-Zaher, Ramzia I. El-Bagary and Gabor Patonay
Analytical Chemistry Insights 2014:9 33-40
Original Research | Published on 07 May 2014

A UPLC–MS Method for the Determination of Ofloxacin Concentrations in Aqueous Humor
Panagiotis Plotas, Charalampos Anastasopoulos, Olga E. Makri, Michalis Leotsinidis and Constantine D. Georgakopoulos
Analytical Chemistry Insights 2014:9 27-32
Methodology | Published on 05 May 2014

Application of Nanofiber-packed SPE for Determination of Urinary 1-Hydroxypyrene Level Using HPLC
Okechukwu Clinton Ifegwu, Chimezie Anyakora, Samuel Chigome and Nelson Torto
Analytical Chemistry Insights 2014:9 17-25
Original Research | Published on 22 Apr 2014

Buprenorphine and Norbuprenorphine Determination in Mice Plasma and Brain by Gas Chromatography–Mass Spectrometry
Fouad Chiadmi and Joël Schlatter
Analytical Chemistry Insights 2014:9 9-16
Rapid Communication | Published on 10 Mar 2014

Synthesis and Characterization of Maillard Reaction Products of Salbutamol and Terbutaline with Lactose and Development and Validation of an LC Method for the Determination of Salbutamol and Terbutaline in the Presence of These Impurities
Asmaa A. El-Zaher, Marwa A. Fouad and Ehab F. Elkady
Analytical Chemistry Insights 2014:9 1-7
Original Research | Published on 02 Mar 2014

Simultaneous Determination of Amlodipine Besylate and Atorvastatin Calcium in Binary Mixture by Spectrofluorimetry and HPLC Coupled with Fluorescence Detection
Bahia A. Moussa, Asmaa A. El-Zaher, Marianne A. Mahrouse and Maha S. Ahmed
Analytical Chemistry Insights 2013:8 107-115
Original Research | Published on 04 Nov 2013

Development and Validation of RP-LC Method for the Determination of Cinnarizine/Piracetam and Cinnarizine/Heptaminol Acefyllinate in Presence of Cinnarizine Reported Degradation Products
Ola M. EL-Houssini, Nagwan H. Zawilla and Mohammad A. Mohammad
Analytical Chemistry Insights 2013:8 99-106
Original Research | Published on 07 Oct 2013

The Evaluation of Two Commercially Available, Portable Raman Systems
Pamela A. Mosier-Boss and Michael D. Putnam
Analytical Chemistry Insights 2013:8 83-97
Review | Published on 10 Sep 2013

RP-LC and TLC Densitometric Determination of Paracetamol and Pamabrom in Presence of Hazardous Impurity of Paracetamol and Application to Pharmaceuticals
Ola Mohamed El-Houssini
Analytical Chemistry Insights 2013:8 73-81
Original Research | Published on 05 Sep 2013

Development of Methods for the Determination of pKa Values
Jetse Reijenga, Arno van Hoof, Antonie van Loon and Bram Teunissen
Analytical Chemistry Insights 2013:8 53-71
Review | Published on 08 Aug 2013

Biochemical Characteristics of Organic Matter in a Guano Concretion of Late Miocene or Pliocene Age from Manchester Parish in Jamaica
Adrian Spence, Richard E. Hanson, Toni Johnson, Claion Robinson and Richard N. Annells
Analytical Chemistry Insights 2013:8 41-52
Original Research | Published on 18 Jun 2013

Evidence for the Presence of 1,3-Dimethylamylamine (1,3-DMAA) in Geranium Plant Materials
Thomas D. Gauthier
Analytical Chemistry Insights 2013:8 29-40
Consise Review | Published on 06 Jun 2013

Determination of the Antiretroviral Drug Acyclovir in Diluted Alkaline Electrolyte by Adsorptive Stripping Voltammetry at the Mercury Film Electrode
Arnaldo Aguiar Castro, Ana Isa Perez Cordoves, and Percio Augusto Mardini Farias
Analytical Chemistry Insights 2013:8 21-28
Original Research | Published on 20 May 2013

Utility of Experimental Design in Pre-Column Derivatization for the Analysis of Tobramycin by HPLC—Fluorescence Detection: Application to Ophthalmic Solution and Human Plasma
Asmaa A. El-Zaher and Marianne A. Mahrouse
Analytical Chemistry Insights 2013:8 9-20
Original Research | Published on 16 Apr 2013

A Rapid Stability-Indicating RP-HPLC Method for the Determination of Betaxolol Hydrochloride in Pharmaceutical Tablets
Sylvain Auvity, Fouad Chiadmi, Salvatore Cisternino, Jean-Eudes Fontan and Joël Schlatter
Analytical Chemistry Insights 2013:8 1-7
Rapid Communication | Published on 11 Mar 2013

Evaluation of Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry for Second-Generation Lignin Analysis
Aurore Richel, Caroline Vanderghem, Mathilde Simon, Bernard Wathelet and Michel Paquot
Analytical Chemistry Insights 2012:7 79-89
Original Research | Published on 13 Dec 2012

Analysis and Confirmation of 1,3-DMAA and 1,4-DMAA in Geranium Plants Using High Performance Liquid Chromatography with Tandem Mass Spectrometry at ng/g Concentrations
Heather L. Fleming, Patricia L. Ranaivo and Paul S. Simone
Analytical Chemistry Insights 2012:7 59-78
Original Research | Published on 08 Nov 2012 | Video abstract

Identification and Quantification of Dimethylamylamine in Geranium by Liquid Chromatography Tandem Mass Spectrometry
J.S. Li, M. Chen and Z.C. Li
Analytical Chemistry Insights 2012:7 47-58
Rapid Communication | Published on 06 Aug 2012

Simultaneous Determination of Sitagliptin and Metformin in Pharmaceutical Preparations by Capillary Zone Electrophoresis and its Application to Human Plasma Analysis
Mohamed Salim, Nahed El-Enany, Fathallah Belal, Mohamed Walash and Gabor Patonay
Analytical Chemistry Insights 2012:7 31-46
Original Research | Published on 30 Jul 2012

A Calculation Model for Serum Ionized Calcium Based on an Equilibrium Equation for Complexation
Susumu Takano, Hiroshi Kaji, Fujio Hayashi, Kanae Higashiguchi, Sachie Joukei, Yoshiaki Kido, Juro Takahashi and Kayo Osawa
Analytical Chemistry Insights 2012:7 23-30
Original Research | Published on 04 Jul 2012

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