Cancer Informatics

An international, peer reviewed, open access journal that focuses on reporting bioinformatic analysis of molecular genetic and/or clinical data pertaining to human cancer risk, prevention, outcome or treatment response.  The journal recognizes that scientific collaborations across traditional disciplines can yield exponential synergistic gains: cancer research benefits from advances in many fields, including genomics and proteomics, mass spectrometry and radio imaging, computer science and biostatistics including machine learning and artificial intelligence, and medical informatics. The journal also recognizes the centrality of computational biology in these synergies.

Editor in Chief: Dr. J. T. Efird

ISSN: 1176-9351

Processing Speed: High quality, constructive peer review and rapid editorial decision within an average of four weeks.

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Gene-Set Reduction for Analysis of Major and Minor Gleason Scores Based on Differential Gene-Set Expressions and Biological Pathways in Prostate Cancer
Irina Dinu, Surya Poudel, Saumyadipta Pyne
Cancer Informatics 2017:16 1176935117730016
Original Research | Published on 11 Sep 2017

xSyn: A Software Tool for Identifying Sophisticated 3-Way Interactions From Cancer Expression Data
Baishali Bandyopadhyay, Veda Chanda, Yupeng Wang
Cancer Informatics 2017:16 1176935117728516
Methodology | Published on 28 Aug 2017

Adaptive Multiview Nonnegative Matrix Factorization Algorithm for Integration of Multimodal Biomedical Data
Bisakha Ray, Wenke Liu, David Fenyö
Cancer Informatics 2017:16 1176935117725727
Methodology | Published on 18 Aug 2017

Immuno-Oncology Integrative Networks: Elucidating the Influences of Osteosarcoma Phenotypes
Ankush Sharma, Enrico Capobianco
Cancer Informatics 2017:16 1176935117721691
Original Research | Published on 26 Jul 2017
This article is part of the special collection Precision Cancer Medicine through Biomedical Informatics

Prediction With Dimension Reduction of Multiple Molecular Data Sources for Patient Survival
Adam Kaplan, Eric F Lock
Cancer Informatics 2017:16 1176935117718517
Methodology | Published on 11 Jul 2017

The Impact of Collisions on the Ability to Detect Rare Mutant Alleles Using Barcode-Type Next-Generation Sequencing Techniques
Jenna VanLiere Canzoniero, Karen Cravero, Ben Ho Park
Cancer Informatics 2017:16 1176935117719236
Original Research | Published on 10 Jul 2017

An Assessment of Database-Validated microRNA Target Genes in Normal Colonic Mucosa: Implications for Pathway Analysis
Martha L Slattery, Jennifer S Herrick, John R Stevens, Roger K Wolff, Lila E Mullany
Cancer Informatics 2017:16 1176935117716405
Original Research | Published on 23 Jun 2017

A Software Application for Mining and Presenting Relevant Cancer Clinical Trials per Cancer Mutation
Lisa M Gandy, Jordan Gumm, Amanda L Blackford, Elana J Fertig, Luis A Diaz
Cancer Informatics 2017:16 1176935117711940
Original Research | Published on 22 Jun 2017

The Model-Based Study of the Effectiveness of Reporting Lists of Small Feature Sets Using RNA-Seq Data
Eunji Kim, Ivan Ivanov, Jianping Hua, Johanna W Lampe, Meredith AJ Hullar, Robert S Chapkin, Edward R Dougherty
Cancer Informatics 2017:16 1176935117710530
Methodology | Published on 12 Jun 2017

Tumor RAS Gene Expression Levels Are Influenced by the Mutational Status of RAS Genes and Both Upstream and Downstream RAS Pathway Genes
Robert M Stephens, Ming Yi, Bailey Kessing, Dwight V Nissley, Frank McCormick
Cancer Informatics 2017:16 1176935117711944
Original Research | Published on 08 Jun 2017

Lung Cancer Pathological Image Analysis Using a Hidden Potts Model
Qianyun Li, Faliu Yi, Tao Wang, Guanghua Xiao, Faming Liang
Cancer Informatics 2017:16 1176935117711910
Original Research | Published on 05 Jun 2017

Immune Checkpoint Inhibition and the Prevalence of Autoimmune Disorders Among Patients With Lung and Renal Cancer
Sherif M El-Refai, Joshua D Brown, Esther P Black, Jeffery C Talbert
Cancer Informatics 2017:16 1176935117712520
Original Research | Published on 01 Jun 2017

Sequence Analysis and Phylogenetic Studies of Hypoxia-Inducible Factor-1α
Jagadeesha Poyya, Chandrashekhar G Joshi, D Jagadeesha Kumar, HG Nagendra
Cancer Informatics 2017:16 1176935117712242
Original Research | Published on 31 May 2017

Quantitative Study of Thermal Disturbances Due to Nonuniformly Perfused Tumors in Peripheral Regions of Women’s Breast
Akshara Makrariya, Neeru Adlakha
Cancer Informatics 2017:16 1176935117700894
Original Research | Published on 15 May 2017

Time-Based Switching Control of Genetic Regulatory Networks: Toward Sequential Drug Intake for Cancer Therapy
Wasiu Opeyemi Oduola, Xiangfang Li, Chang Duan, Lijun Qian, Fen Wu, Edward R Dougherty
Cancer Informatics 2017:16 1176935117706888
Review | Published on 10 May 2017
This article is part of the special collection Precision Cancer Medicine through Biomedical Informatics

Applying Multivariate Adaptive Splines to Identify Genes With Expressions Varying After Diagnosis in Microarray Experiments
Fenghai Duan, Ye Xu
Cancer Informatics 2017:16 1176935117705381
Review | Published on 04 May 2017

miR-10a and miR-204 as a Potential Prognostic Indicator in Low-Grade Gliomas
Ju Cheol Son, Hyoung Oh Jeong, Deaui Park, Sang Gyoon No, Eun Kyeong Lee, Jaewon Lee, Hae Young Chung
Cancer Informatics 2017:16 1176935117702878
Original Research | Published on 12 Apr 2017

A mixture copula Bayesian network model for multimodal genomic data
Qingyang Zhang, Xuan Shi
Cancer Informatics 2017:16 1176935117702389
Methodology | Published on 12 Apr 2017

Bioinformatics Education in Pathology Training: Current Scope and Future Direction
Michael R Clay, Kevin E Fisher
Cancer Informatics 2017:16 1176935117703389
Review | Published on 10 Apr 2017
This article is part of the special collection Sequencing for the Masses: Another Desktop Revolution

Therapeutic Interventions of Cancers Using Intrinsically Disordered Proteins as Drug Targets: c-Myc as Model System
Deepak Kumar, Nitin Sharma, Rajanish Giri
Cancer Informatics 2017:16 1176935117699408
Review | Published on 16 Mar 2017

Roadmap to a Comprehensive Clinical Data Warehouse for Precision Medicine Applications in Oncology
David J Foran, Wenjin Chen, Huiqi Chu, Evita Sadimin, Doreen Loh, Gregory Riedlinger, Lauri A Goodell, Shridar Ganesan, Kim Hirshfield, Lorna Rodriguez, Robert S DiPaola
Cancer Informatics 2017:16 1176935117694349
Original Research | Published on 02 Mar 2017

Integrative Analysis of Gene Networks and Their Application to Lung Adenocarcinoma Studies
Sangin Lee, Faming Liang, Ling Cai, Guanghua Xiao
Cancer Informatics 2017:16 1176935117690778
Original Research | Published on 23 Feb 2017

Significant Prognostic Features and Patterns of Somatic Mutations in Human Cancers
Wensheng Zhang, Andrea Edwards, Erik K Flemington, Kun Zhang
Cancer Informatics 2017:16 1176935117691267
Original Research | Published on 20 Feb 2017
This article is part of the special collection Precision Cancer Medicine through Biomedical Informatics

Improving Gastric Cancer Outcome Prediction Using Single Time-Point Artificial Neural Network Models
Hamid Nilsaz-Dezfouli, Mohd Rizam Abu-Bakar, Jayanthi Arasan, Mohd Bakri Adam, Mohamad Amin Pourhoseingholi
Cancer Informatics 2017:16 1176935116686062
Original Research | Published on 16 Feb 2017

A Numerical Handling of the Boundary Conditions Imposed by the Skull on an Inhomogeneous Diffusion-Reaction Model of Glioblastoma Invasion Into the Brain: Clinical Validation Aspects
Georgios S Stamatakos, Stavroula G Giatili
Cancer Informatics 2017:16 1176935116684824
Original Research | Published on 03 Feb 2017

Epithelial Ovarian Cancer Diagnosis of Second-Harmonic Generation Images: A Semiautomatic Collagen Fibers Quantification Protocol
Angel A Zeitoune, Johana SJ Luna, Kynthia Sanchez Salas, Luciana Erbes, Carlos L Cesar, Liliana ALA Andrade, Hernades F Carvahlo, Fátima Bottcher-Luiz, Victor H Casco, Javier Adur
Cancer Informatics 2017:16 1176935117690162
Original Research | Published on 03 Feb 2017

Unified Least Squares Methods for the Evaluation of Diagnostic Tests With the Gold Standard
Liansheng Larry Tang, Ao Yuan, John Collins, Xuan Che, Leighton Chan
Cancer Informatics 2017:16 1176935116686063
Review | Published on 03 Feb 2017
This article is part of the special collection Computer Simulation, Bioinformatics, and Statistical Analysis of Cancer Data and Processes

Bayesian ABC-MCMC Classification of Liquid Chromatography–Mass Spectrometry Data
Upamanyu Banerjee and Ulisses M. Braga-Neto
Cancer Informatics 2015:Suppl. 5 175-182
Methodology | Published on 09 Jan 2017

Identification of Genetic and Epigenetic Variants Associated with Breast Cancer Prognosis by Integrative Bioinformatics Analysis
Arunima Shilpi, Yingtao Bi, Segun Jung, Samir K. Patra and Ramana V. Davuluri
Cancer Informatics 2017:16 1-13
Original Research | Published on 09 Jan 2017

A Novel Optical Bioimaging Method for Direct Assessment of Ovarian Cancer Chemotherapy Response at Laparoscopy
Alexandros Laios, Davide Volpi, Rajeev Kumar, Zoe Traill, Borivoj Vojnovic and Ahmed A. Ahmed
Cancer Informatics 2016:15 243-245
Short Report | Published on 08 Jan 2017

ROC Estimation from Clustered Data with an Application to Liver Cancer Data
Joungyoun Kim, Sung-Cheol Yun, Johan Lim, Moo-Song Lee, Won Son and DoHwan Park
Cancer Informatics 2016:Suppl. 4 19-26
Original Research | Published on 22 Dec 2016
This article is part of the special collection Computer Simulation, Bioinformatics, and Statistical Analysis of Cancer Data and Processes

Quantitative Proteomic Approach for MicroRNA Target Prediction Based on 18O/16O Labeling
Xuepo Ma, Ying Zhu, Yufei Huang, Tony Tegeler, Shou-Jiang Gao and Jianqiu Zhang
Cancer Informatics 2015:Suppl. 5 163-173
Original Research | Published on 08 Dec 2016

Comparison of Three Information Sources for Smoking Information in Electronic Health Records
Liwei Wang, Xiaoyang Ruan, Ping Yang and Hongfang Liu
Cancer Informatics 2016:15 237-242
Original Research | Published on 08 Dec 2016

A Modular Repository-based Infrastructure for Simulation Model Storage and Execution Support in the Context of In Silico Oncology and In Silico Medicine
Nikolaos A. Christodoulou, Nikolaos E. Tousert, Eleni Ch. Georgiadi, Katerina D. Argyri, Fay D. Misichroni and Georgios S. Stamatakos
Cancer Informatics 2016:15 219-235
Original Research | Published on 27 Oct 2016

Discovering Outliers of Potential Drug Toxicities Using a Large-scale Data-driven Approach
Jake Luo and Ron A. Cisler
Cancer Informatics 2016:15 211-217
Original Research | Published on 26 Oct 2016

Cluster Analysis of p53 Binding Site Sequences Reveals Subsets with Different Functions
Ji-Hyun Lim, Natasha S. Latysheva, Richard D. Iggo, and Daniel Barker
Cancer Informatics 2016:15 199-209
Original Research | Published on 25 Oct 2016

A Novel Graph-based Algorithm to Infer Recurrent Copy Number Variations in Cancer
Chen Chi, Rasif Ajwad, Qin Kuang and Pingzhao Hu
Cancer Informatics 2016:Suppl. 2 43-50
Methodology | Published on 09 Oct 2016

Discovering MicroRNA-Regulatory Modules in Multi-Dimensional Cancer Genomic Data: A Survey of Computational Methods
Christopher J. Walsh, Pingzhao Hu, Jane Batt, and Claudia C. dos Santos
Cancer Informatics 2016:Suppl. 2 25-42
Review | Published on 03 Oct 2016

Novel Biomarker Candidates for Colorectal Cancer Metastasis: A Meta-analysis of In Vitro Studies
Nguyen Phuoc Long, Wun Jun Lee, Nguyen Truong Huy, Seul Ji Lee, Jeong Hill Park and Sung Won Kwon
Cancer Informatics 2016:Suppl. 4 11-17
Original Research | Published on 22 Sep 2016
This article is part of the special collection Computer Simulation, Bioinformatics, and Statistical Analysis of Cancer Data and Processes

Identifying Significant Features in Cancer Methylation Data Using Gene Pathway Segmentation
Zena M. Hira and Duncan F. Gillies
Cancer Informatics 2016:15 189-198
Methodology | Published on 20 Sep 2016

Overlapping Group Logistic Regression with Applications to Genetic Pathway Selection
Yaohui Zeng and Patrick Breheny
Cancer Informatics 2016:15 179-187
Methodology | Published on 15 Sep 2016

DNA Methylation Heterogeneity Patterns in Breast Cancer Cell Lines
Sunny Tian, Karina Bertelsmann, Linda Yu and Shuying Sun
Cancer Informatics 2016:Suppl. 4 1-9
Original Research | Published on 07 Sep 2016
This article is part of the special collection Computer Simulation, Bioinformatics, and Statistical Analysis of Cancer Data and Processes

Biological Networks for Cancer Candidate Biomarkers Discovery
Wenying Yan, Wenjin Xue, Jiajia Chen and Guang Hu
Cancer Informatics 2016:Suppl. 3 1-7
Review | Published on 04 Sep 2016
This article is part of the special collection Precision Cancer Medicine through Biomedical Informatics

Characterization of Gene Expression Patterns among Artificially Developed Cancer Stem Cells Using Spherical Self-Organizing Map
Akimasa Seno, Tomonari Kasai, Masashi Ikeda, Arun Vaidyanath, Junko Masuda, Akifumi Mizutani, Hiroshi Murakami, Tetsuya Ishikawa and Masaharu Seno
Cancer Informatics 2016:15 163-178
Original Research | Published on 16 Aug 2016

ExSurv: A Web Resource for Prognostic Analyses of Exons Across Human Cancers Using Clinical Transcriptomes
Seyedsasan Hashemikhabir, Gungor Budak and Sarath Chandra Janga
Cancer Informatics 2016:Suppl. 2 17-24
Technical Advance | Published on 07 Aug 2016 | Video abstract

Pathway-Informed Classification System (PICS) for Cancer Analysis Using Gene Expression Data
Michael R Young, and David L Craft
Cancer Informatics 2016:15 151-161
Original Research | Published on 27 Jul 2016

Recursive Partitioning Method on Competing Risk Outcomes
Wei Xu, Jiahua Che, and Qin Kong
Cancer Informatics 2016:Suppl. 2 9-16
Methodology | Published on 26 Jul 2016

Normalized lmQCM: An Algorithm for Detecting Weak Quasi-Cliques in Weighted Graph with Applications in Gene Co-Expression Module Discovery in Cancers
Jie Zhang and Kun Huang
Cancer Informatics 2014:Suppl. 3 137-146
Original Research | Published on 24 Jul 2016

TMAinspiration: Decode Interdependencies in Multifactorial Tissue Microarray Data
Florian Boecker, Horst Buerger, Nikhil V. Mallela and Eberhard Korsching
Cancer Informatics 2016:15 143-149
Methodology | Published on 29 Jun 2016

An Integrated Approach for RNA-seq Data Normalization
Shengping Yang, Donald E. Mercante, Kun Zhang and Zhide Fang
Cancer Informatics 2016:15 129-141
Original Research | Published on 27 Jun 2016

The Melanoma MAICare Framework: A Microsimulation Model for the Assessment of Individualized Cancer Care
Elisabeth van der Meijde, Alfons J. M. van den Eertwegh, Sabine C. Linn, Gerrit A. Meijer, Remond J. A. Fijneman, and Veerle M. H. Coupé
Cancer Informatics 2016:15 115-127
Original Research | Published on 15 Jun 2016

multiClust: An R-package for Identifying Biologically Relevant Clusters in Cancer Transcriptome Profiles
Nathan Lawlor, Alec Fabbri, Peiyong Guan, Joshy George and R. Krishna Murthy Karuturi
Cancer Informatics 2016:15 103-114
Software or Database Review | Published on 12 Jun 2016

A Novel Approach to Predict Core Residues on Cancer-Related DNA-Binding Domains
Ka-Chun Wong
Cancer Informatics 2016:Suppl. 2 1-7
Original Research | Published on 02 Jun 2016

Rational Design of Peptide Vaccines Against Multiple Types of Human Papillomavirus
Sumanta Dey, Antara De and Ashesh Nandy
Cancer Informatics 2016:Suppl. 1 1-16
Original Research | Published on 01 Jun 2016 | Video abstract

A Bayesian Nonparametric Approach for Functional Data Classification with Application to Hepatic Tissue Characterization
Kassandra M. Fronczyk, Michele Guindani, Brian P. Hobbs, Chaan S. Ng and Marina Vannucci
Cancer Informatics 2015:Suppl. 5 151-162
Original Research | Published on 29 May 2016

Bioinformatic Studies to Predict MicroRNAs with the Potential of Uncoupling RECK Expression from Epithelial–Mesenchymal Transition in Cancer Cells
Zhipeng Wang, Ryusuke Murakami, Kanako Yuki, Yoko Yoshida and Makoto Noda
Cancer Informatics 2016:15 91-102
Original Research | Published on 19 May 2016

Selecting Reliable mRNA Expression Measurements Across Platforms Improves Downstream Analysis
Pan Tong, Lixia Diao, Li Shen, Lerong Li, John Victor Heymach, Luc Girard, John D. Minna, Kevin R. Coombes, Lauren Averett Byers and Jing Wang
Cancer Informatics 2016:15 81-89
Original Research | Published on 10 May 2016

Thyroid Cancer and Tumor Collaborative Registry (TCCR)
Oleg Shats, Whitney Goldner, Jianmin Feng, Alexander Sherman, Russell B. Smith and Simon Sherman
Cancer Informatics 2016:15 73-79
Technical Advance | Published on 03 May 2016

A New Approach for Identification of Cancer-related Pathways using Protein Networks and Genomic Data
André Fonseca, Marco D. Gubitoso, Marcelo S. Reis, Sandro J. de Souza, and Junior Barrera
Cancer Informatics 2015:Suppl. 5 139-149
Original Research | Published on 02 May 2016

RefCNV: Identification of Gene-Based Copy Number Variants Using Whole Exome Sequencing
Lun-Ching Chang, Biswajit Das, Chih-Jian Lih, Han Si, Corinne E. Camalier, Paul M. McGregor III and Eric Polley
Cancer Informatics 2016:15 65-71
Methodology | Published on 27 Apr 2016

Immunomediated Pan-cancer Regulation Networks are Dominant Fingerprints After Treatment of Cell Lines with Demethylation
Mariama El Baroudi, Caterina Cinti and Enrico Capobianco
Cancer Informatics 2016:15 45-64
Original Research | Published on 27 Apr 2016

Data Requirements for Model-Based Cancer Prognosis Prediction
Lori A. Dalton and Mohammadmahdi R. Yousefi
Cancer Informatics 2015:Suppl. 5 123-138
Original Research | Published on 21 Apr 2016

High-Dimensional Statistical Learning: Roots, Justifications, and Potential Machineries
Amin Zollanvari
Cancer Informatics 2015:Suppl. 5 109-121
Review | Published on 12 Apr 2016

Flow Cytometry-Based Classification in Cancer Research: A View on Feature Selection
S. Sakira Hassan, Pekka Ruusuvuori, Leena Latonen and Heikki Huttunen
Cancer Informatics 2015:Suppl. 5 75-85
Original Research | Published on 10 Apr 2016

An NGS Workflow Blueprint for DNA Sequencing Data and Its Application in Individualized Molecular Oncology
Jian Li, Aarif Mohamed Nazeer Batcha, Björn Grüning and Ulrich R. Mansmann
Cancer Informatics 2015:Suppl. 5 87-107
Original Research | Published on 10 Apr 2016 | Video abstract

Unraveling the Deleterious Effects of Cancer-Driven STK11 Mutants Through Conformational Sampling Approach
Merlin Lopus, D. Meshach Paul and R. Rajasekaran
Cancer Informatics 2016:15 35-44
Original Research | Published on 04 Apr 2016

Design of Probabilistic Random Forests with Applications to Anticancer Drug Sensitivity Prediction
Raziur Rahman, Saad Haider, Souparno Ghosh and Ranadip Pal
Cancer Informatics 2015:Suppl. 5 57-73
Original Research | Published on 31 Mar 2016

Integrative Analysis of mRNA, microRNA, and Protein Correlates of Relative Cerebral Blood Volume Values in GBM Reveals the Role for Modulators of Angiogenesis and Tumor Proliferation
Arvind Rao, Ganiraju Manyam, Ganesh Rao and Rajan Jain
Cancer Informatics 2016:15 29-33
Original Research | Published on 29 Mar 2016

Optimized Prediction of Extreme Treatment Outcomes in Ovarian Cancer
Burook Misganaw, Eren Ahsen, Nitin Singh, Keith A. Baggerly, Anna Unruh, Michael A. White and M. Vidyasagar
Cancer Informatics 2015:Suppl. 5 45-55
Original Research | Published on 21 Mar 2016

Assessing Combinational Drug Efficacy in Cancer Cells by Using Image-based Dynamic Response Analysis
Chao Sima, Jianping Hua, Milana Cypert, Tasha Miller, Heather M. Wilson-Robles, Jeffrey M. Trent, Edward R. Dougherty and Michael L. Bittner
Cancer Informatics 2015:Suppl. 5 33-43
Original Research | Published on 09 Mar 2016

Detection of Productively Rearranged TcR-α V–J Sequences in TCGA Exome Files: Implications for Tumor Immunoscoring and Recovery of Antitumor T-cells
Thomas R. Gill, Mohammad D. Samy, Shanitra N. Butler, James A. Mauro, Wade J. Sexton and George Blanck
Cancer Informatics 2016:15 23-28
Rapid Communication | Published on 25 Feb 2016

Toward Signaling-Driven Biomarkers Immune to Normal Tissue Contamination
John C. Stansfield, Matthew Rusay, Roger Shan, Conor Kelton, Daria A. Gaykalova, Elana J. Fertig, Joseph A. Califano, and Michael F. Ochs
Cancer Informatics 2016:15 15-21
Original Research | Published on 10 Feb 2016

Correlation between Gene Variants, Signaling Pathways, and Efficacy of Chemotherapy Drugs against Colon Cancers
Swarnendu Tripathi, Louiza Belkacemi, Margaret S. Cheung and Rathindra N. Bose
Cancer Informatics 2016:15 1-13
Original Research | Published on 20 Jan 2016

Integrating Multiscale Modeling with Drug Effects for Cancer Treatment
Xiangfang L. Li, Wasiu O. Oduola, Lijun Qian and Edward R. Dougherty
Cancer Informatics 2015:Suppl. 5 21-31
Review | Published on 13 Jan 2016

Introductory Editorial: Computer Simulation, Visualization, and Image Processing of Cancer Data and Processes
David Johnson, James Osborne, Zhihui Wang, Kostas Marias
Cancer Informatics 2015:Suppl. 4 105-108
Editorial | Published on 12 Jan 2016

Simulation of the Protein-Shedding Kinetics of a Fully Vascularized Tumor
Hermann B. Frieboes, Louis T. Curtis, Min Wu, Kian Kani and Parag Mallick
Cancer Informatics 2015:14 163-175
Original Research | Published on 20 Dec 2015

Improving Cancer Gene Expression Data Quality through a TCGA Data-Driven Evaluation of Identifier Filtering
Kevin K. McDade, Uma Chandran and Roger S. Day
Cancer Informatics 2015:14 149-161
Original Research | Published on 16 Dec 2015

Differential Expression Analysis for RNA-Seq: An Overview of Statistical Methods and Computational Software
Huei-Chung Huang, Yi Niu, and Li-Xuan Qin
Cancer Informatics 2015:Suppl. 1 57-67
Review | Published on 13 Dec 2015

The Impact of Age and Sex in DLBCL: Systems Biology Analyses Identify Distinct Molecular Changes and Signaling Networks
Afshin Beheshti, Donna Neuberg, J. Tyson McDonald, Charles R. Vanderburg and Andrew M. Evens
Cancer Informatics 2015:14 141-148
Rapid Communication | Published on 10 Dec 2015

Predictive Modeling of Drug Treatment in the Area of Personalized Medicine
Lesley A. Ogilvie, Christoph Wierling, Thomas Kessler, Hans Lehrach, and Bodo M. H. Lange
Cancer Informatics 2015:Suppl. 4 95-103
Commentary | Published on 06 Dec 2015

Characterizing Cancer-Specific Networks by Integrating TCGA Data
Yanxun Xu, Yitan Zhu, Peter Müller, Riten Mitra and Yuan Ji
Cancer Informatics 2014:Suppl. 2 125-131
Methodology | Published on 23 Nov 2015

Multigroup Equivalence Analysis for High-Dimensional Expression Data
Celeste Yang, Alfred A. Bartolucci and Xiangqin Cui
Cancer Informatics 2015:Suppl. 2 253-263
Methodology | Published on 23 Nov 2015

Multivariate Boosting for Integrative Analysis of High-Dimensional Cancer Genomic Data
Lie Xiong, Pei-Fen Kuan, Jianan Tian, Sunduz Keles, and Sijian Wang
Cancer Informatics 2014:Suppl. 7 123-131
Methodology | Published on 15 Nov 2015

Cancer Bioinformatic Methods to Infer Meaningful Data From Small-Size Cohorts
Nabila Bennani-Baiti and Idriss M. Bennani-Baiti
Cancer Informatics 2015:14 131-139
Review | Published on 02 Nov 2015

Effectiveness and Usability of Bioinformatics Tools to Analyze Pathways Associated with miRNA Expression
Lila E. Mullany, Roger K. Wolff and Martha L. Slattery
Cancer Informatics 2015:14 121-130
Original Research | Published on 29 Oct 2015

Publication Bias in Methodological Computational Research
Anne-Laure Boulesteix, Veronika Stierle and Alexander Hapfelmeier
Cancer Informatics 2015:Suppl. 5 11-19
Methodology | Published on 15 Oct 2015

FXYD5 is a Marker for Poor Prognosis and a Potential Driver for Metastasis in Ovarian Carcinomas
Pichai Raman, Timothy Purwin, Richard Pestell and Aydin Tozeren
Cancer Informatics 2015:14 113-119
Short Report | Published on 12 Oct 2015

Multiscale Model of Colorectal Cancer Using the Cellular Potts Framework
James M. Osborne
Cancer Informatics 2015:Suppl. 4 83-93
Original Research | Published on 04 Oct 2015

TIN: An R Package for Transcriptome Instability Analysis
Bjarne Johannessen, Anita Sveen, and Rolf I. Skotheim
Cancer Informatics 2015:14 109-112
Software or database review | Published on 20 Sep 2015

Alview: Portable Software for Viewing Sequence Reads in BAM Formatted Files
Richard P. Finney, Qing-Rong Chen, Cu V. Nguyen, Chih Hao Hsu, Chunhua Yan, Ying Hu, Massih Abawi, Xiaopeng Bian and Daoud M. Meerzaman
Cancer Informatics 2015:14 105-107
Software or database review | Published on 13 Sep 2015

An Application of Sequential Meta-Analysis to Gene Expression Studies
Putri W. Novianti, Ingeborg van der Tweel, Victor L. Jong, Kit C. B. Roes and Marinus J. C. Eijkemans
Cancer Informatics 2015:Suppl. 5 1-10
Methodology | Published on 10 Sep 2015

The Importance of Neighborhood Scheme Selection in Agent-based Tumor Growth Modeling
Georgios Tzedakis, Eleftheria Tzamali, Kostas Marias and Vangelis Sakkalis
Cancer Informatics 2015:Suppl. 4 67-81
Original Research | Published on 07 Sep 2015

Preprocessing Steps for Agilent MicroRNA Arrays: Does the Order Matter?
Li-Xuan Qin, Huei-Chung Huang and Qin Zhou
Cancer Informatics 2014:Suppl. 4 105-109
Original Research | Published on 03 Sep 2015

Introductory Editorial: Computer Simulation, Bioinformatics, and Statistical Analysis of Cancer Data and Processes
Kellie J. Archer, Kevin Dobbin, Swati Biswas, Roger S. Day, David C. Wheeler, Hao Wu
Cancer Informatics 2015:Suppl. 2 247-251
Editorial | Published on 01 Sep 2015

CoGNaC: A Chaste Plugin for the Multiscale Simulation of Gene Regulatory Networks Driving the Spatial Dynamics of Tissues and Cancer
Simone Rubinacci, Alex Graudenzi, Giulio Caravagna, Giancarlo Mauri, James Osborne, Joe Pitt-Francis and Marco Antoniotti
Cancer Informatics 2015:Suppl. 4 53-65
Technical Advance | Published on 01 Sep 2015

Assessing Treatment Response Through Generalized Pharmacokinetic Modeling of DCE-MRI Data
Eleftherios Kontopodis, Georgia Kanli, Georgios C. Manikis, Sofie Van Cauter and Kostas Marias
Cancer Informatics 2015:Suppl. 4 41-51
Original Research | Published on 12 Aug 2015

In Silico Neuro-Oncology: Brownian Motion-Based Mathematical Treatment as a Potential Platform for Modeling the Infiltration of Glioma Cells into Normal Brain Tissue
Markos Antonopoulos and Georgios Stamatakos
Cancer Informatics 2015:Suppl. 4 33-40
Review | Published on 10 Aug 2015

HMPL: A Pipeline for Identifying Hemimethylation Patterns by Comparing Two Samples
Shuying Sun and Peng Li
Cancer Informatics 2015:Suppl. 2 235-245
Original Research | Published on 09 Aug 2015

Secondary Data Analytics of Aquaporin Expression Levels in Glioblastoma Stem-Like Cells
Raphael D. Isokpehi, Katharina C. Wollenberg Valero, Barbara E. Graham, Maricica Pacurari, Jennifer N. Sims, Udensi K. Udensi and Kenneth Ndebele
Cancer Informatics 2015:14 95-103
Original Research | Published on 30 Jul 2015

Medical Image Retrieval: A Multimodal Approach
Yu Cao, Shawn Steffey, Jianbiao He, Degui Xiao, Cui Tao, Ping Chen and Henning Müller
Cancer Informatics 2014:Suppl. 3 125-136
Original Research | Published on 22 Jul 2015

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