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JOURNAL

Biomarker Insights


An international, peer reviewed, open access journal that aims to support those engaged in biomarker research, by providing rapid communication of the latest advances in the application of biomarkers toward discovery of new knowledge and clinical application of that knowledge.

Editor in Chief: Dr. Karen Pulford

ISSN: 1177-2719

Processing Speed: High quality, constructive peer review and rapid editorial decision within an average of four weeks.



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2017:12

Soluble P-selectin as a Biomarker for Infection and Survival in Patients With a Systemic Inflammatory Response Syndrome on the Intensive Care Unit
Irene T. Schrijver, Hans. Kemperman, Mark. Roest, Jozef. Kesecioglu, Dylan W. de Lange
Biomarker Insights 2017:12 1177271916684823
Original research | Published on 07 Feb 2017



Cytochrome P-450 1B1 Leu432Val Polymorphism Does Not Show Association With Breast Cancer in Northern Iranian Women With a History of Infertility
Maryam Ghanbari. Andarieh, Ebrahim. Zabihi, Dariush. Moslemi, Mouloud Agajani. Delavar, Mahmoud. Haji-Ahmadi, Ali Shabestani. Monfared, Seyed Gholam Ali. Jorsaraei, Masoumeh. Ghasemi, Sedighe. Esmaeilzadeh
Biomarker Insights 2017:12 1177271916689058
Original research | Published on 20 Feb 2017



Expression of Reactive Oxygen Species–Related Transcripts in Egyptian Children With Autism
Nagwa A. Meguid, Said A S. Ghozlan, Magda F. Mohamed, Marwa K. Ibrahim, Reham M. Dawood, Noha G. Bader El Din, Tawfeek H. Abdelhafez, Maha. Hemimi, Mostafa K. El Awady
Biomarker Insights 2017:12 1177271917691035
Original research | Published on 23 Feb 2017



A Novel Biomarker Panel to Identify Steroid Resistance in Childhood Idiopathic Nephrotic Syndrome
Michael R. Bennett, LaTawnya. Pleasant, Christopher. Haffner, Qing. Ma, Wendy D. Haffey, Jun. Ying, Michael. Wagner, Kenneth D. Greis, Prasad. Devarajan
Biomarker Insights 2017:12 1177271917695832
Original research | Published on 08 Mar 2017



An Integrative Genomics Approach for Associating Genome-Wide Association Studies Information With Localized and Metastatic Prostate Cancer Phenotypes
Chindo. Hicks, Ritika. Ramani, Oliver. Sartor, Ritu. Bhalla, Lucio. Miele, Zodwa. Dlamini, Njabulo. Gumede
Biomarker Insights 2017:12 1177271917695810
Original research | Published on 16 Mar 2017



Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge
Maria. Vergoulidou
Biomarker Insights 2017:12 1177271917695237
Original research | Published on 16 Mar 2017



2016:11

Urinary Vitamin D-Binding Protein as a Biomarker of Steroid-Resistant Nephrotic Syndrome
Michael R. Bennett, Angad Pordal, Christopher Haffner, LaTawnya Pleasant, Qing Ma and Prasad Devarajan
Biomarker Insights 2016:11 1-6
Original research | Published on 13 Jan 2016



Isolation of Circulating Tumor Cells from Multiple Epithelial Cancers with ApoStream for Detecting (or Monitoring) the Expression of Folate Receptor Alpha
Daniel J. O'Shannessy, Darren W. Davis, Kenna Anderes and Elizabeth B. Somers
Biomarker Insights 2016:11 7-18
Original research | Published on 01 Feb 2016



DNA Subtraction of In Vivo Selected Phage Repertoires for Efficient Peptide Pathology Biomarker Identification in Neuroinflammation Multiple Sclerosis Model
Karina Vargas-Sanchez, Antonios Vekris, and Klaus G. Petry
Biomarker Insights 2016:11 19-29
Original research | Published on 16 Feb 2016



Assessment of Neutrophil Gelatinase-Associated Lipocalin (NGAL) and Retinol-Binding Protein 4 (RBP4) in Type 2 Diabetic Patients with Nephropathy
Mohamed H. Mahfouz, Adel M. Assiri and Mohammed H. Mukhtar
Biomarker Insights 2016:11 31-40
Original research | Published on 16 Feb 2016



Urine Proteome Biomarkers in Kidney Diseases. I. Limits, Perspectives, and First Focus on Normal Urine
Laura Santucci, Maurizio Bruschi, Giovanni Candiano, Francesca Lugani, Andrea Petretto, Alice Bonanni and Gian Marco Ghiggeri
Biomarker Insights 2016:11 41-48
Original research | Published on 16 Mar 2016



Heme Oxygenase Activity Correlates with Serum Indices of Iron Homeostasis in Healthy Nonsmokers
Andrew J. Ghio and Dina M. Schreinemachers
Biomarker Insights 2016:11 49-54
Original research | Published on 19 Apr 2016



Proteomic Changes in the Plasma of Broiler Chickens with Femoral Head Necrosis
Balamurugan Packialakshmi, Rohana Liyanage, Jackson O. Lay, Jr., Ronald Okimoto and Narayan C. Rath
Biomarker Insights 2016:11 55-62
Original research | Published on 27 Apr 2016



Evaluation of Ischemia-Modified Albumin, Malondialdehyde, and Advanced Oxidative Protein Products as Markers of Vascular Injury in Diabetic Nephropathy
Afzal Ahmad, Poornima Manjrekar, Charu Yadav, Ashish Agarwal, Rukmini Mysore Srikantiah and Anupama Hegde
Biomarker Insights 2016:11 63-68
Original research | Published on 02 May 2016



Prediction of the Risk for Essential Hypertension among Carriers of C825T Genetic Polymorphism of G Protein β3 (GNB3) Gene
Neveen Salah El Din Hemimi, Amal A. Mansour and Mona Mohamed Abdelsalam
Biomarker Insights 2016:11 69-75
Original research | Published on 17 May 2016



Precision-Cut Kidney Slices as a Tool to Understand the Dynamics of Extracellular Matrix Remodeling in Renal Fibrosis
Federica Genovese, Zsolt S. Kàrpàti, Signe H. Nielsen and Morten A. Karsdal
Biomarker Insights 2016:11 77-84
Original research | Published on 22 May 2016



Role of Biomarkers in the Diagnosis, Risk Assessment, and Management of Pulmonary Hypertension
Vanessa Rameh and Antoine Kossaify
Biomarker Insights 2016:11 85-89
Original research | Published on 23 Jun 2016



Changes in Urinary and Serum Levels of Novel Biomarkers after Administration of Gadolinium-based Contrast Agents
Habib Mawad, Louis-Philippe Laurin, Jean-François Naud, François A. Leblond, Nathalie Henley, Michel Vallée, Vincent Pichette and Martine Leblanc
Biomarker Insights 2016:11 91-94
Original research | Published on 29 Jun 2016



Significance of HbA1c Test in Diagnosis and Prognosis of Diabetic Patients
Shariq I. Sherwani, Haseeb A. Khan, Aishah Ekhzaimy, Afshan Masood and Meena K. Sakharkar
Biomarker Insights 2016:11 95-104
Original research | Published on 03 Jul 2016



Plasminogen Activator System and Breast Cancer: Potential Role in Therapy Decision Making and Precision Medicine
Adel Gouri, Aoulia Dekaken, Khalid El Bairi, Arifa Aissaoui, Nihad Laabed, Mohamed Chefrour, Joseph Ciccolini, Gérard Milano and Sadek Benharkat
Biomarker Insights 2016:11 105-111
Original research | Published on 16 Aug 2016



Low Doses of Cisplatin Induce Gene Alterations, Cell Cycle Arrest, and Apoptosis in Human Promyelocytic Leukemia Cells
Venkatramreddy Velma, Shaloam R. Dasari and Paul B. Tchounwou
Biomarker Insights 2016:11 113-121
Original research | Published on 24 Aug 2016



Procalcitonin Is a Better Biomarker than C-Reactive Protein in Newborns Undergoing Cardiac Surgery: The PROKINECA Study
Sara Bobillo Pérez, Javier Rodríguez-Fanjul, Iolanda Jordan García, Julio Moreno Hernando and Martín Iriondo Sanz
Biomarker Insights 2016:11 123-129
Original research | Published on 03 Nov 2016



Asymmetric Dimethylarginine and Its Relation As a Biomarker in Nephrologic Diseases
Mustafa E. Sitar
Biomarker Insights 2016:11 131-137
Original research | Published on 07 Dec 2016



Prognostic Value of MammaPrint® in Invasive Lobular Breast Cancer
Inès J. Beumer, Marion Persoon, Anke Witteveen, Christa Dreezen, Suet-Feung Chin, Stephen-John Sammut, Mireille Snel, Carlos Caldas, Sabine Linn, Laura J. van 't Veer, Rene Bernards and Annuska M. Glas
Biomarker Insights 2016:11 139-146
Original research | Published on 11 Dec 2016



A Comparison of Different Methodologies for the Measurement of Extracellular Vesicles and Milk-derived Particles in Raw Milk from Cows
Geoff Pollott, Amanda Brito, Christopher Gardiner and Charlotte Lawson
Biomarker Insights 2016:11 147-155
Original research | Published on 13 Dec 2016



2016:Suppl. 1

Beyond the Ribosome: Extra-translational Functions of tRNA Fragments
Kevin W. Diebel, Kun Zhou, Aaron B. Clarke and Lynne T. Bemis
Biomarker Insights 2016:Suppl. 1 1-8
Original research | Published on 28 Jan 2016



2015:10

Prednisolone-Induced Predisposition to Femoral Head Separation and the Accompanying Plasma Protein Changes in Chickens
B Packialakshmi, R Liyanage, JO Lay, Jr, R Okimoto and NC Rath
Biomarker Insights 2015:10 1-8
Original research | Published on 14 Jan 2015



Perchlorate Exposure is Associated with Oxidative Stress and Indicators of Serum Iron Homeostasis Among NHANES 2005–2008 Subjects
Dina M. Schreinemachers, Andrew J. Ghio, Jon R. Sobus and Marc A. Williams
Biomarker Insights 2015:10 9-19
Original research | Published on 28 Jan 2015



MicroRNA-Seq Data Analysis Pipeline to Identify Blood Biomarkers for Alzheimer's Disease from Public Data
Jun-ichi Satoh, Yoshihiro Kino and Shumpei Niida
Biomarker Insights 2015:10 21-31
Original research | Published on 15 Apr 2015



Polymorphism in Variable Number of Tandem Repeats of Dopamine D4 Gene Is a Genetic Risk Factor in Attention Deficit Hyperactive Egyptian Children: Pilot Study
Ola Shahin, Nagwa A. Meguid, Omnia Raafat, Reham M. Dawood, Malak Doss, Noha G. Bader el Din and Mostafa K. El Awady
Biomarker Insights 2015:10 33-38
Original research | Published on 05 May 2015



Literature-Based Discovery of Salivary Biomarkers for Type 2 Diabetes Mellitus
Mythily Srinivasan, Corinne Blackburn, Mohamed Mohamed, A.V. Sivagami and Janice Blum
Biomarker Insights 2015:10 39-45
Original research | Published on 14 May 2015



Immunomodulatory Effects of Probiotic Supplementation in Schizophrenia Patients: A Randomized, Placebo-Controlled Trial
Jakub Tomasik, Robert H. Yolken, Sabine Bahn, and Faith B. Dickerson
Biomarker Insights 2015:10 47-54
Original research | Published on 01 Jun 2015



Analysis of Lung Flute–collected Sputum for Lung Cancer Diagnosis
Jian Su, Nigar Anjuman, Maria A. Guarnera, Howard Zhang, Sanford A. Stass and Feng Jiang
Biomarker Insights 2015:10 55-61
Original research | Published on 04 Aug 2015



Autoantibody Profiles in Collagen Disease Patients with Interstitial Lung Disease (ILD): Antibodies to Major Histocompatibility Complex Class I-Related Chain A (MICA) as Markers of ILD
Hiroshi Furukawa, Shomi Oka, Kota Shimada, Kiyoe Masuo, Fumiaki Nakajima, Shunichi Funano, Yuki Tanaka, Akiko Komiya, Naoshi Fukui, Tatsuya Sawasaki, Kenji Tadokoro, Masato Nose, Naoyuki Tsuchiya and Shigeto Tohma
Biomarker Insights 2015:10 63-73
Original research | Published on 16 Aug 2015



von Willebrand Factor Propeptide: A Potential Disease Biomarker Not Affected by ABO Blood Groups
Mahat Marianor, Abdullah Wan Zaidah and C.H. Che Maraina
Biomarker Insights 2015:10 75-79
Original research | Published on 23 Aug 2015



Urinary Neutrophil Gelatinase-Associated Lipocalin to Monitor Lupus Nephritis Disease Activity
Hani Susianti, Jullyanny W. Wijaya, Ati Rastini, Kusworini Handono, Atma Gunawan and Handono Kalim
Biomarker Insights 2015:10 81-87
Original research | Published on 06 Sep 2015



Decreased Phosphorylated Protein Kinase B (Akt) in Individuals with Autism Associated with High Epidermal Growth Factor Receptor (EGFR) and Low Gamma-Aminobutyric Acid (GABA)
Anthony J. Russo
Biomarker Insights 2015:10 89-94
Original research | Published on 14 Oct 2015



MicroRNA-155 and Its Role in Malignant Hematopoiesis
Prajnya Ranganath
Biomarker Insights 2015:10 95-102
Original research | Published on 22 Oct 2015



High Expression of Three-Gene Signature Improves Prediction of Relapse-Free Survival in Estrogen Receptor-Positive and Node-Positive Breast Tumors
Arvind Thakkar, Hemanth Raj, Ravishankar, Bhaskaran Muthuvelan, Arun Balakrishnan and Muralidhara Padigaru
Biomarker Insights 2015:10 103-112
Original research | Published on 30 Nov 2015



miRNAs As Diagnostic and Prognostic Biomarkers in Pancreatic Ductal Adenocarcinoma and Its Precursor Lesions: A Review
Bárbara Alemar, Cleandra Gregório, and Patricia Ashton-Prolla
Biomarker Insights 2015:10 113-124
Original research | Published on 13 Dec 2015



Patterns of Local and Systemic Cytokines in Bacterial Meningitis and its Relation with Severity and Long-Term Sequelae
Federico Perdomo-Celis, Miguel A. Torres, Henry Ostos, Javier Gutierrez-Achury, Víctor Molano, Luis F. Durán, Guillermo González, and Carlos F. Narváez
Biomarker Insights 2015:10 125-131
Original research | Published on 20 Dec 2015



2015:Suppl. 1 Stem Cell Biology

The Roles of Neuregulin-1 in Cardiac Development, Homeostasis, and Disease
Cassady E. Rupert and Kareen L.K. Coulombe
Biomarker Insights 2015:Suppl. 1 1-9
Original research | Published on 08 Apr 2015



Gene Delivery Strategies to Promote Spinal Cord Repair
Christopher M. Walthers and Stephanie K. Seidlits
Biomarker Insights 2015:Suppl. 1 11-29
Original research | Published on 09 Apr 2015



From “Directed Differentiation” to “Neuronal Induction”: Modeling Neuropsychiatric Disease
Seok-Man Ho, Aaron Topol and Kristen J. Brennand
Biomarker Insights 2015:Suppl. 1 31-41
Original research | Published on 27 Apr 2015



Endogenous Repair Signaling after Brain Injury and Complementary Bioengineering Approaches to Enhance Neural Regeneration
Caroline P. Addington, Adam Roussas, Dipankar Dutta and Sarah E. Stabenfeldt
Biomarker Insights 2015:Suppl. 1 43-60
Original research | Published on 12 May 2015



Optimizing Differentiation Protocols for Producing Dopaminergic Neurons from Human Induced Pluripotent Stem Cells for Tissue Engineering Applications
Meghan Robinson, Suk-yu Yau, Lin Sun, Nicole Gabers, Emma Bibault, Brian R. Christie and Stephanie M. Willerth
Biomarker Insights 2015:Suppl. 1 61-70
Original research | Published on 26 May 2015



Differentiation of Cardiomyocytes from Human Pluripotent Stem Cells Using Monolayer Culture
Ivan Batalov and Adam W. Feinberg
Biomarker Insights 2015:Suppl. 1 71-76
Original research | Published on 27 May 2015



Biomaterial Approaches for Stem Cell-Based Myocardial Tissue Engineering
Josh Cutts, Mehdi Nikkhah and David A. Brafman
Biomarker Insights 2015:Suppl. 1 77-90
Original research | Published on 01 Jun 2015



Prospects for In Vitro Myofilament Maturation in Stem Cell-Derived Cardiac Myocytes
Jonas Schwan and Stuart G. Campbell
Biomarker Insights 2015:Suppl. 1 91-103
Original research | Published on 10 Jun 2015



Synthetic Extracellular Microenvironment for Modulating Stem Cell Behaviors
Prafulla Chandra and Sang Jin Lee
Biomarker Insights 2015:Suppl. 1 105-116
Original research | Published on 17 Jun 2015



Self-organized Kidney Rudiments: Prospects for Better in vitro Nephrotoxicity Assays
Jamie A. Davies
Biomarker Insights 2015:Suppl. 1 117-123
Original research | Published on 16 Jul 2015



Applications of iPSCs in Cancer Research
Jean J. Kim
Biomarker Insights 2015:Suppl. 1 125-131
Original research | Published on 29 Jul 2015



Introductory Editorial: Stem Cell Biology
David Brafman, Stuart Campbell, Albert Q. Lam, Jean J. Kim, Mehdi Nikkhah, Sarah Stabenfeldt
Biomarker Insights 2015:Suppl. 1 133-137
Original research | Published on 23 Aug 2015



Stem Cells and Progenitor Cells for Tissue-Engineered Solutions to Congenital Heart Defects
Yang Gao and Jeffrey G. Jacot
Biomarker Insights 2015:Suppl. 1 139-146
Original research | Published on 26 Aug 2015



Directed Differentiation of Pluripotent Stem Cells into Kidney
Ryuji Morizane and Albert Q. Lam
Biomarker Insights 2015:Suppl. 1 147-152
Original research | Published on 13 Sep 2015



Modeling Kidney Disease with iPS Cells
Benjamin S. Freedman
Biomarker Insights 2015:Suppl. 1 153-169
Original research | Published on 22 Dec 2015



2015:Suppl. 2 Autoimmune Diseases

Serum Neopterin Levels Among Hepatitis C-Positive Living-Donor Renal Transplant Recipients
Shivali Justa, Ranjana W. Minz, Shashi Anand and Mukut Minz
Biomarker Insights 2015:Suppl. 2 1-6
Original research | Published on 01 Jun 2015



2015:Suppl. 3 Tyrosine Kinases in Cancer

Class III Receptor Tyrosine Kinases in Acute Leukemia – Biological Functions and Modern Laboratory Analysis
Rimma Berenstein
Biomarker Insights 2015:Suppl. 3 1-14
Original research | Published on 05 Aug 2015



Role of Tyrosine Kinase Inhibitors in Indolent and Other Mature B-Cell Neoplasms
Nadine Kutsch, Reinhard Marks, Richard Ratei, Thomas K. Held and Martin Schmidt-Hieber
Biomarker Insights 2015:Suppl. 3 15-23
Original research | Published on 16 Aug 2015



BCR-ABL Mutation-Guided Therapy for CML Blast Crisis: A Case Report
Benjamin N. Ostendorf, Hendrik Nogai, Claudia D. Baldus, Thomas Burmeister, and Renate Arnold
Biomarker Insights 2015:Suppl. 3 25-28
Original research | Published on 30 Aug 2015



Emerging Role of Tyrosine Kinases as Drugable Targets in Cancer
Il-Kang Na and Philipp le Coutre
Biomarker Insights 2015:Suppl. 3 29-31
Original research | Published on 10 Sep 2015



More than a Decade of Tyrosine Kinase Inhibitors in the Treatment of Solid Tumors: What We Have Learned and What the Future Holds
Maria Vergoulidou
Biomarker Insights 2015:Suppl. 3 33-40
Original research | Published on 08 Oct 2015



Introductory Editorial: Tyrosine Kinases in Cancer
Olga Blau, Boris Afanasyev, Igor W. Blau
Biomarker Insights 2015:Suppl. 3 41-42
Original research | Published on 02 Nov 2015



Efficacy of Dasatinib in a CML Patient in Blast Crisis with F317L Mutation: A Case Report and Literature Review
E.V. Morozova, Y.Y. Vlasova, M.V. Pryanishnikova, K.V. Lepik and B.V. Afanasyev
Biomarker Insights 2015:Suppl. 3 43-47
Original research | Published on 08 Dec 2015



Management of Chronic Myeloid Leukemia Patients Resistant to Tyrosine Kinase Inhibitors Treatment
Agnieszka Wieczorek and Lutz Uharek
Biomarker Insights 2015:Suppl. 3 49-54
Original research | Published on 18 Feb 2016



Risk of Infectious Complications in Hemato-Oncological Patients Treated with Kinase Inhibitors
Mark Reinwald, Tobias Boch, Wolf-Karsten Hofmann and Dieter Buchheidt
Biomarker Insights 2015:Suppl. 3 55-68
Original research | Published on 21 Apr 2016



2015:Suppl. 4 Gene and Protein Expression Profiling in Disease

Genomic, Proteomic, and Metabolomic Data Integration Strategies
Kwanjeera Wanichthanarak, Johannes F. Fahrmann and Dmitry Grapov
Biomarker Insights 2015:Suppl. 4 1-6
Original research | Published on 07 Sep 2015 | Editor in Chief endorsed



Biomarkers for Sepsis: What Is and What Might Be?
Bethany M. Biron, Alfred Ayala and Joanne L. Lomas-Neira
Biomarker Insights 2015:Suppl. 4 7-17
Original research | Published on 15 Sep 2015



Evaluation of Candidate Biomarkers of Type 1 Diabetes via the Core for Assay Validation
Cate Speake and Jared M. Odegard
Biomarker Insights 2015:Suppl. 4 19-24
Original research | Published on 29 Sep 2015



MicroRNAs Expressed during Viral Infection: Biomarker Potential and Therapeutic Considerations
Jennifer Louten, Michael Beach, Kristina Palermino, Maria Weeks and Gabrielle Holenstein
Biomarker Insights 2015:Suppl. 4 25-52
Original research | Published on 18 Jan 2016



Bioinformatics Resources for MicroRNA Discovery
Alyssa C. Moore, Jonathan S. Winkjer and Tsai-Tien Tseng
Biomarker Insights 2015:Suppl. 4 53-58
Original research | Published on 18 Jan 2016



Challenges and Current Efforts in the Development of Biomarkers for Chronic Inflammatory and Remodeling Conditions of the Lungs
Gabriele Grunig, Aram Baghdassarian, Sung-Hyun Park, Serhiy Pylawka, Bertram Bleck, Joan Reibman, Erika Berman-Rosenzweig and Nedim Durmus
Biomarker Insights 2015:Suppl. 4 59-72
Original research | Published on 16 Feb 2016 | Video Abstract Available



Histone H3 Phosphorylation in Human Skin Histoculture as a Tool to Evaluate Patient’s Response to Antiproliferative Drugs
Fernando Ugarte, Katherine Porth and Svetlana Sadekova
Biomarker Insights 2015:Suppl. 4 73-76
Original research | Published on 18 Feb 2016



2014:9

Utility of C-terminal Telopeptide in Evaluating Levothyroxine Replacement Therapy-Induced Bone Loss
Alap L. Christy, Vivian D’Souza, Ruby P. Babu, Sohil Takodara, Poornima Manjrekar, Anupama Hegde and M. S. Rukmini
Biomarker Insights 2014:9 1-6
Original research | Published on 03 Mar 2014



Comment on "Validation of a Blood-Based Laboratory Test to Aid in the Confirmation of a Diagnosis of Schizophrenia"
Stephen F. Kingsmore
Biomarker Insights 2014:9 7
Original research | Published on 23 Mar 2014



The Range of Uncertainty: a Tool for Efficiently Addressing Result Variability Around Clinical Decision Points for Hepatitis C Response-Guided Therapy
Paul Jülicher and Jens Dhein
Biomarker Insights 2014:9 9-13
Original research | Published on 09 Apr 2014



Prognostic Value of DNA and mRNA E6/E7 of Human Papillomavirus in the Evolution of Cervical Intraepithelial Neoplasia Grade 2
Michelle G. Discacciati, Ismael DCG da Silva, Luisa L. Villa, Leandro Reis, Priscila Hayashi, Maria C. Costa, Silvia H. Rabelo-Santos and Luiz C. Zeferino
Biomarker Insights 2014:9 15-22
Original research | Published on 13 Apr 2014



HLA-DRB1*08:02 Is Associated with Bucillamine-Induced Proteinuria in Japanese Rheumatoid Arthritis Patients
Hiroshi Furukawa, Shomi Oka, Kota Shimada, Shoji Sugii, Atsushi Hashimoto, Akiko Komiya, Naoshi Fukui, Taiichiro Miyashita, Kiyoshi Migita, Akiko Suda, Shouhei Nagaoka, Naoyuki Tsuchiya and Shigeto Tohma
Biomarker Insights 2014:9 23-28
Original research | Published on 19 May 2014



Folate Receptor Alpha, Mesothelin and Megakaryocyte Potentiating Factor as Potential Serum Markers of Chronic Kidney Disease
Elizabeth B. Somers and Daniel J. O’Shannessy
Biomarker Insights 2014:9 29-37
Original research | Published on 25 May 2014



Integrative Genomic Analysis for the Discovery of Biomarkers in Prostate Cancer
Chindo Hicks, Tejaswi Koganti, Shankar Giri, Memory Tekere, Ritika Ramani, Jitsuda Sitthi-Amorn and Srinivasan Vijayakumar
Biomarker Insights 2014:9 39-51
Original research | Published on 29 Jun 2014



DNA Methylation at the Novel CpG Sites in the Promoter of MED15/PCQAP Gene as a Biomarker for Head and Neck Cancers
Dmitry A. Ovchinnikov, Yunxia Wan, William B. Coman, Pratibala Pandit, Justin J. Cooper-White, James G. Herman and Chamindie Punyadeera
Biomarker Insights 2014:9 53-60
Original research | Published on 03 Jul 2014 | Video Abstract Available



Hydroxyproline, a Serum Biomarker Candidate for Gastric Ulcer in Rats: A Comparison Study of Metabolic Analysis of Gastric Ulcer Models Induced by Ethanol, Stress, and Aspirin
Kenichiro Takeuchi, Maki Ohishi, Keiko Endo, Kenichi Suzumura, Hitoshi Naraoka, Takeji Ohata, Jiro Seki, Yoichi Miyamae, Masashi Honma and Tomoyoshi Soga
Biomarker Insights 2014:9 61-66
Original research | Published on 27 Jul 2014



Identification of Gene Signatures Used to Recognize Biological Characteristics of Gastric Cancer Upon Gene Expression Data
Zhi Yan, Brian T. Luke, Shirley X. Tsang, Rui Xing, Yuanming Pan, Yixuan Liu, Jinlian Wang, Tao Geng, Jiangeng Li and Youyong Lu
Biomarker Insights 2014:9 67-76
Original research | Published on 14 Aug 2014



Increased Expression of Phosphorylated FADD in Anaplastic Large Cell and Other T-Cell Lymphomas
Suketu Patel, Derek Murphy, Eugenia Haralambieva, Zainalabideen A Abdulla, Kah Keng Wong, Hong Chen, Edith Gould, Giovanna Roncador, Chris SR Hatton, Amanda P Anderson, Alison H Banham and Karen Pulford
Biomarker Insights 2014:9 77-84
Original research | Published on 03 Sep 2014



Decreased Mitogen Inducible Gene 6 (MIG-6) Associated with Symptom Severity in Children with Autism
AJ Russo
Biomarker Insights 2014:9 85-89
Original research | Published on 06 Oct 2014



Risk Factors Associated with Serum Levels of the Inflammatory Biomarker Soluble Urokinase Plasminogen Activator Receptor in a General Population
Thomas H. Haupt, Thomas Kallemose, Steen Ladelund, Line J. H. Rasmussen, Christian W. Thorball, Ove Andersen, Charlotta Pisinger and Jesper Eugen-Olsen
Biomarker Insights 2014:9 91-100
Original research | Published on 16 Dec 2014



2013:8

Lipid Profile of Patients with Acute Myocardial Infarction and its Correlation with Systemic Inflammation
Haseeb A. Khan, Abdullah S. Alhomida and Samia H. Sobki
Biomarker Insights 2013:8 1-7
Original research | Published on 24 Jan 2013



Personalized Medicine in Screening for Malignant Disease: A Review of Methods and Applications
F. Schmalfuss and P.L. Kolominsky-Rabas
Biomarker Insights 2013:8 9-14
Original research | Published on 18 Feb 2013



Urine Biomarkers Neutrophil Gelatinase-Associated Lipocalin (NGAL) and Kidney Injury Molecule-1 (KIM-1) have Different Patterns in Heart Failure Exacerbation
Meyeon Park, Eric Vittinghoff, Kathleen D. Liu, Michael G. Shlipak, and Chi-yuan Hsu
Biomarker Insights 2013:8 15-18
Original research | Published on 11 Mar 2013



Quantitative Appraisal of Ventricular Cerebrospinal Fluid Biomarkers in Neuropathologically Diagnosed Parkinson's Disease Cases Lacking Alzheimer's Disease Pathology
Chera L. Maarouf, Thomas G. Beach, Charles H. Adler, Michael Malek-Ahmadi, Tyler A. Kokjohn, Brittany N. Dugger, Douglas G. Walker, Holly A. Shill, Sandra A. Jacobson, Marwan N. Sabbagh, Alex E. Roher and Arizona Parkinson’s Disease Consortium
Biomarker Insights 2013:8 19-28
Original research | Published on 12 Mar 2013



A Further Study of the Role of Copper in Regard to the Antimutagenic Action of Sodium Copper Chlorophyllin (SCC) in Somatic Cells of Drosophila melanogaster
Emilio Pimentel, Martha P. Cruces and Stanley Zimmering
Biomarker Insights 2013:8 29-33
Original research | Published on 12 Mar 2013



Decreased Epidermal Growth Factor (EGF) Associated with HMGB1 and Increased Hyperactivity in Children with Autism
Anthony J. Russo
Biomarker Insights 2013:8 35-41
Original research | Published on 04 Apr 2013



Oxidative Stress and DNA Damage Induced by Chromium in Liver and Kidney of Goldfish, Carassius auratus
Venkatramreddy Velma and Paul B. Tchounwou
Biomarker Insights 2013:8 43-51
Original research | Published on 25 Apr 2013



Biomarkers of Dose and Effect of Inhaled Ozone in Resting versus Exercising Human Subjects: Comparison with Resting Rats
Gary E. Hatch, John McKee, James Brown, William McDonnell, Elston Seal, Joleen Soukup, Ralph Slade, Kay Crissman and Robert Devlin
Biomarker Insights 2013:8 53-67
Original research | Published on 19 May 2013



Correlation Between Hepatocyte Growth Factor (HGF) and Gamma-Aminobutyric Acid (GABA) Plasma Levels in Autistic Children
Anthony J. Russo
Biomarker Insights 2013:8 69-75
Original research | Published on 12 Jun 2013



CIINE Reflects Collagenase-Specific CII Breakdown in Cartilage Explant and Whole Body of Canine
Satoko Matsukawa, Miki Tanimura, Tomoko Toyosaki-Maeda, Akihiro Noda, Mika Kobayashi, Akira Yamauchi, Junji Onoda, Toshinaga Tsuji, Tatsuya Takahashi, Yoshiyuki Matsuo and Naoshi Fukui
Biomarker Insights 2013:8 77-83
Original research | Published on 16 Jun 2013



Identification of Potential Prognostic Markers for Knee Osteoarthritis by Serum Proteomic Analysis
Yoshihiko Takinami, Shinya Yoshimatsu, Takaoki Uchiumi, Tomoko Toyosaki-Maeda, Atsushi Morita, Takeshi Ishihara, Shoji Yamane, Isao Fukuda, Hiroyuki Okamoto, Yoshito Numata and Naoshi Fukui
Biomarker Insights 2013:8 85-95
Original research | Published on 29 Jul 2013



Markers that can Reflect Asthmatic Activity before and after Reduction of Inhaled Corticosteroids: A Pilot Study
Go Kato, Koichiro Takahashi, Kenji Izuhara, Kazutoshi Komiya, Shinya Kimura and Shinichiro Hayashi
Biomarker Insights 2013:8 97-105
Original research | Published on 04 Aug 2013



Decreased Hepatocyte Growth Factor (HGF) and Gamma Aminobutyric Acid (GABA) in Individuals with Obsessive-Compulsive Disorder (OCD)
Anthony J. Russo and Stefanie C. Pietsch
Biomarker Insights 2013:8 107-114
Original research | Published on 18 Aug 2013



Perspectives on the Value of Biomarkers in Acute Cardiac Care and Implications for Strategic Management
Antoine Kossaify, Annie Garcia, Sami Succar, Antoine Ibrahim, Nicolas Moussallem, Mikhael Kossaify and Gilles Grollier, STAR-P Consortium
Biomarker Insights 2013:8 115-126
Original research | Published on 03 Sep 2013



Quantification of Plasma miRNAs by Digital PCR for Cancer Diagnosis
Jie Ma, Ning Li, Maria Guarnera and Feng Jiang
Biomarker Insights 2013:8 127-136
Original research | Published on 14 Nov 2013



2012:7

Overcoming the Effects of Matrix Interference in the Measurement of Urine Protein Analytes
Timothy P. Taylor, Michael G. Janech, Elizabeth H. Slate, Evelyn C. Lewis, John M. Arthur, and Jim C Oates
Biomarker Insights 2012:7 1-8
Original research | Published on 01 Feb 2012



Detection of 1p19q Deletion by Real-Time Comparative Quantitative PCR
Abhishek Chaturbedi, Liping Yu, Mark E Linskey and Yi-hong Zhou
Biomarker Insights 2012:7 9-17
Original research | Published on 01 Feb 2012



Evaluation of Ischemia-Modified Albumin and C-Reactive Protein in Type 2 Diabetics With and Without Ketosis
Shao-gang Ma, Yao Jin, Wen Hu, Feng Bai, Wen Xu and Wei-nan Yu
Biomarker Insights 2012:7 19-26
Original research | Published on 14 Mar 2012



Increased Levels of Circulating and Tissue mRNAs of Oct-4, Sox-2, Bmi-1 and Nanog is ESCC Patients: Potential Tool for Minimally Invasive Cancer Diagnosis
Kriti Bahl, Anoop Saraya and Rinu Sharma
Biomarker Insights 2012:7 27-37
Original research | Published on 26 Mar 2012



The Prognostic Value of suPAR Compared to Other Inflammatory Markers in Patients with Severe Sepsis
Anna Gustafsson, Lennart Ljunggren, Mikael Bodelsson and Ingrid Berkestedt
Biomarker Insights 2012:7 39-44
Original research | Published on 10 Apr 2012



Novel Cardiac-Specific Biomarkers and the Cardiovascular Continuum
Efstathios Vassiliadis, Natasha Barascuk, Athanasios Didangelos and Morten A Karsdal
Biomarker Insights 2012:7 45-57
Original research | Published on 02 May 2012



Prognosis of Treatment Response (Pathological Complete Response) in Breast Cancer
Jason B. Nikas, Walter C. Low and Paul A. Burgio
Biomarker Insights 2012:7 59-70
Original research | Published on 08 May 2012



Characterization of Antibodies that Detect Human GFAP after Traumatic Brain Injury
J. Susie Zoltewicz, Dancia Scharf, Boxuan Yang, Aarti Chawla, Kimberly J. Newsom and Lijuan Fang
Biomarker Insights 2012:7 71-79
Original research | Published on 25 Jun 2012



Circulating Immune Complex Levels are Associated with Disease Severity and Seasonality in Children with Malaria from Mali
Bolaji N. Thomas, Dapa A. Diallo, Ghislain T. Noumsi and Joann M. Moulds
Biomarker Insights 2012:7 81-86
Original research | Published on 03 Jul 2012



Biomarkers of Disease and Treatment in Murine and Cynomolgus Models of Chronic Asthma
Jennifer Louten, Jeanine D. Mattson, Maria-Christina Malinao, Ying Li, Claire Emson, Felix Vega, Robert L. Wardle, Michael R. Van Scott, Robert B. Fick, Terrill K. McClanahan, Rene de Waal Malefyt and Maribel Beaumont
Biomarker Insights 2012:7 87-104
Original research | Published on 10 Jul 2012



Molecular Serum Markers of Liver Fibrosis
Tianhui Liu, Xiaoming Wang, Morten A. Karsdal, Diana J. Leeming and Federica Genovese
Biomarker Insights 2012:7 105-117
Original research | Published on 23 Jul 2012



Serological Investigation of the Collagen Degradation Profile of Patients with Chronic Obstructive Pulmonary Disease or Idiopathic Pulmonary Fibrosis
Diana J. Leeming, Jannie M. Sand, Mette J. Nielsen, Federica Genovese, Fernando J. Martinez, Cory M. Hogaboam, MeiLan K Han, Lloyd B. Klickstein and Morten A. Karsdal
Biomarker Insights 2012:7 119-126
Original research | Published on 13 Sep 2012



Knowledge Building Insights on Biomarkers of Arsenic Toxicity to Keratinocytes and Melanocytes
Raphael D. Isokpehi, Udensi K. Udensi, Matthew N. Anyanwu, Andreas N. Mbah, Matilda O. Johnson, Kafui Edusei, Michael A. Bauer, Roger A. Hall and Omotayo R. Awofolu
Biomarker Insights 2012:7 127-141
Original research | Published on 15 Oct 2012



Associations of Circulating Inflammatory Biomarkers with Risk Factors for Colorectal Cancer in Colorectal Adenoma Patients
Myfanwy H. Hopkins, W. Dana Flanders and Roberd M. Bostick
Biomarker Insights 2012:7 143-150
Original research | Published on 05 Nov 2012



Variants in the Signaling Protein TSAd are Associated with Susceptibility to Ovarian Cancer in BRCA1/2 Negative High Risk Families
Ludmila Kaplun, Aviva Levine Fridman, Wei Chen, Nancy K. Levin, Sidra Ahsan, Nancie Petrucelli, Jennifer L. Barrick, Robin Gold, Susan Land, Michael S. Simon, Robert T. Morris, Adnan R. Munkarah and Michael A. Tainsky
Biomarker Insights 2012:7 151-157
Original research | Published on 12 Dec 2012



Circulating Levels of a Collagen Type V Propeptide Fragment in a Carbon Tetrachloride Reversible Model of Liver Fibrosis
E. Vassiliadis, S.S. Veidal, C. Hansen, M.A. Karsdal and D.J. Leeming
Biomarker Insights 2012:7 159-166
Original research | Published on 17 Dec 2012



2011:6

Association of Insulin Resistance with Serum Interleukin-6 and TNF-α Levels During Normal Pregnancy
Abdolreza Sotoodeh Jahromi, Parvin Zareian and Abdolhossein Madani
Biomarker Insights 2011:6 1-6
Original research | Published on 12 Jan 2011



Aberrantly Expressed Genes in HaCaT Keratinocytes Chronically Exposed to Arsenic Trioxide
Udensi K. Udensi, Hari H.P. Cohly, Barbara E. Graham-Evans, Kenneth Ndebele, Natàlia Garcia-Reyero, Bindu Nanduri, Paul B. Tchounwou and Raphael D. Isokpehi
Biomarker Insights 2011:6 7-16
Original research | Published on 08 Feb 2011



FXYD3: A Promising Biomarker for Urothelial Carcinoma
ZhongFa Zhang, See-Tong Pang, Katherine A. Kasper, Chunyan Luan, Bill Wondergem, Fan Lin, Cheng-Keng Chuang, Bin Tean Teh and Ximing J. Yang
Biomarker Insights 2011:6 17-26
Original research | Published on 15 Feb 2011



Uncarinic Acid C Isolated from Uncaria rhynchophylla Induces Differentiation of Th1-Promoting Dendritic Cells Through TLR4 Signaling
Kyu Sik Kim, Thanh Nhan Nguyen Pham, Chun-Ji Jin, Akemi Umeyama, Noboru Shoji, Toshihiro Hashimoto, Je-Jung Lee and Masao Takei
Biomarker Insights 2011:6 27-38
Original research | Published on 28 Feb 2011



1H HRMAS NMR Derived Bio-markers Related to Tumor Grade, Tumor Cell Fraction, and Cell Proliferation in Prostate Tissue Samples
Katarina Stenman, Pär Stattin, Hans Stenlund, Katrine Riklund, Gerhard Gröbner and Anders Bergh
Biomarker Insights 2011:6 39-47
Original research | Published on 14 Mar 2011



Measurement of CO3-610, a Potential Liver Biomarker Derived from Matrix Metalloproteinase-9 Degradation of Collagen Type III, in a Rat Model of Reversible Carbon-Tetrachloride-Induced Fibrosis
Efstathios Vassiliadis, Dorthe Vang Larsen, Rikke Elgaard Clausen, Sanne Skovgård Veidal, Natasha Barascuk, Lise Larsen, Henrik Simonsen, Toni Segovia-Silvestre, Christina Hansen, Trine Overgaard, Diana Julie Leeming and Morten A Karsdal
Biomarker Insights 2011:6 49-58
Original research | Published on 24 Mar 2011



Changes in Plasma Fibronectin Isoform Levels Predict Distinct Clinical Outcomes in Critically Ill Patients
John H. Peters, Mark N. Grote, Nancy E. Lane and Richard J. Maunder
Biomarker Insights 2011:6 59-68
Original research | Published on 29 May 2011



Comparison of Liquid Chromatography–Tandem Mass Spectrometry and Sandwich ELISA for Determination of Keratan Sulfate in Plasma and Urine
Jonathan P. Hintze, Shunji Tomatsu, Tadashi Fujii, Adriana M. Montaño, Seiji Yamaguchi, Yasuyuki Suzuki, Masaru Fukushi, Takeshi Ishimaru and Tadao Orii
Biomarker Insights 2011:6 69-78
Original research | Published on 27 Jun 2011



Plasma Soluble Urokinase Plasminogen Activator Receptor in Children with Urinary Tract Infection
Per Wittenhagen, Jesper Brandt Andersen, Anita Hansen, Lone Lindholm, Frederik Rønne, Jørn Theil, Michael Tvede and Jesper Eugen-Olsen
Biomarker Insights 2011:6 79-82
Original research | Published on 16 Aug 2011



Building Multi-Marker Algorithms for Disease Prediction—The Role of Correlations Among Markers
Paul F. Pinsky and Claire S. Zhu
Biomarker Insights 2011:6 83-93
Original research | Published on 14 Aug 2011



Erratum for “Aberrantly Expressed Genes in HaCaT Keratinocytes Chronically Exposed to Arsenic Trioxide”

Udensi K. Udensi, Hari H.P. Cohly, Barbara E. Graham-Evans, Kenneth Ndebele, Natàlia Garcia-Reyero, Bindu Nanduri, Paul B. Tchounwou and Raphael D. Isokpehi


Biomarker Insights 2011:6 95-95
Original research | Published on 08 Sep 2011



Levels of Circulating MMCN-151, a Degradation Product of Mimecan, Reflect Pathological Extracellular Matrix Remodeling in Apolipoprotein E Knockout Mice
N. Barascuk, E. Vassiliadis, Q. Zheng, Y. Wang, W. Wang, L. Larsen, L.M. Rasmussen and M.A. Karsdal
Biomarker Insights 2011:6 97-106
Original research | Published on 22 Sep 2011



The Primary Cilium as a Biomarker in the Hypoxic Adaptation of Bone Marrow-Derived Mesenchymal Stromal Cells: A Role for the Secreted Frizzled-Related Proteins
Sébastien Proulx-Bonneau and Borhane Annabi
Biomarker Insights 2011:6 107-118
Original research | Published on 29 Sep 2011



Detection of suPAR in the Saliva of Healthy Young Adults: Comparison with Plasma Levels
Anna Gustafsson, Vjosa Ajeti and Lennart Ljunggren
Biomarker Insights 2011:6 119-125
Original research | Published on 25 Oct 2011



Analysis of Copper and Zinc Plasma Concentration and the Efficacy of Zinc Therapy in Individuals with Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS) and Autism
A.J. Russo and Robert deVito
Biomarker Insights 2011:6 127-133
Original research | Published on 08 Nov 2011



Association between Perchlorate and Indirect Indicators of Thyroid Dysfunction in Nhanes 2001–2002, a Cross-Sectional, Hypothesis-Generating Study
Dina M. Schreinemachers
Biomarker Insights 2011:6 135-146
Original research | Published on 01 Dec 2011



2010:5

Assessment of Confounding Factors Affecting the Tumor Markers SMRP, CA125, and CYFRA21-1 in Serum
Daniel Gilbert Weber, Georg Johnen, Dirk Taeger, Anne Weber, Isabelle Mercedes Gross, Beate Pesch, Thomas Kraus, Thomas Brüning and Monika Gube
Biomarker Insights 2010:5 1-8
Original research | Published on 28 Jan 2010



Immunohistochemistry as an Important Tool in Biomarkers Detection and Clinical Practice
Leandro Luongo de Matos, Damila Cristina Trufelli, Maria Graciela Luongo de Matos and Maria Aparecida da Silva Pinhal
Biomarker Insights 2010:5 9-20
Original research | Published on 09 Feb 2010



Association of CYP1B1 Polymorphisms with Breast Cancer: A Case-Control Study in the Han Population in Ningxia Hui Autonomous Region, P. R. China
Haiyan Jiao, Chunlian Liu, Weidong Guo, Liang Peng, Yintao Chen and Francis L. Martin
Biomarker Insights 2010:5 21-27
Original research | Published on 12 Feb 2010



The Common FTO Genetic Polymorphism rs9939609 is Associated with Increased BMI in Type 1 Diabetes  but not with Diabetic Nephropathy
Harvest F. Gu, Alexandra Alvarsson and Kerstin Brismar
Biomarker Insights 2010:5 29-32
Original research | Published on 27 Apr 2010



Elevated Serum Sorbitol and not Fructose in Type 2 Diabetic Patients
Gregory M. Preston and Roberto A. Calle
Biomarker Insights 2010:5 33-38
Original research | Published on 04 May 2010



Validation of a Blood-Based Laboratory Test to Aid in the Confirmation of a Diagnosis of Schizophrenia
Emanuel Schwarz, Rauf Izmailov, Michael Spain, Anthony Barnes, James P. Mapes, Paul C. Guest, Hassan Rahmoune, Sandra Pietsch, F. Markus Leweke, Matthias Rothermundt, Johann Steiner, Dagmar Koethe, Laura Kranaster, Patricia Ohrmann, Thomas Suslow, Yishai Levin, Bernhard Bogerts, Nico (JM) van Beveren, George McAllister, Natalya Weber, David Niebuhr, David Cowan, Robert H. Yolken and Sabine Bahn
Biomarker Insights 2010:5 39-47
Original research | Published on 12 May 2010



Feasibility of High-Throughput Genome-Wide Genotyping using DNA from Stored Buccal Cell Samples
Stephanie J. Loomis, Lana M. Olson, Louis R. Pasquale, Janey Wiggs, Daniel Mirel, Andrew Crenshaw, Melissa Parkin, Brandon Rahhal, Stephanie Tetreault, Peter Kraft, Shelley S. Tworoger, Jonathan L. Haines and Jae H. Kang
Biomarker Insights 2010:5 49-55
Original research | Published on 20 May 2010



Detection of Homocysteine and C-Reactive Protein in the Saliva of Healthy Adults: Comparison with Blood Levels
Michael C. Dillon, Daniel C. Opris, Rafal Kopanczyk, Jackie Lickliter, Hayley N. Cornwell, Edward G. Bridges, Andrea M. Nazar and Kristie Grove Bridges
Biomarker Insights 2010:5 57-61
Original research | Published on 02 Jul 2010



Decreased Serum Hepatocyte Growth Factor (HGF) in Individuals with Depression Correlates with Severity of Disease
A.J. Russo
Biomarker Insights 2010:5 63-67

Original research | Published on 03 Aug 2010



LSOSS: Detection of Cancer Outlier Differential Gene Expression
Yupeng Wang and Romdhane Rekaya
Biomarker Insights 2010:5 69-78
Original research | Published on 05 Aug 2010



Standardization of Gene Expression Quantification by Absolute Real-Time qRT-PCR System Using a Single Standard for Marker and Reference Genes
Yi-Hong Zhou, Vinay R. Raj, Eric Siegel and Liping Yu
Biomarker Insights 2010:5 79-85
Original research | Published on 16 Aug 2010



Diagnostic Markers for Tuberculosis Ascites: A Preliminary Study
Rajpal S. Kashyap, Sonali M. Saha, Khushboo J. Nagdev, Sanjeevani S. Kelkar, Hemant J. Purohit, Girdhar M. Taori and Hatim F. Daginawala
Biomarker Insights 2010:5 87-94
Original research | Published on 25 Aug 2010



Assessment of mRNA and microRNA Stabilization in Peripheral Human Blood for Multicenter Studies and Biobanks
Daniel Gilbert Weber, Swaantje Casjens, Peter Rozynek, Martin Lehnert, Sandra Zilch- Schöneweis, Oleksandr Bryk, Dirk Taeger, Maria Gomolka, Michaela Kreuzer, Heinz Otten, Beate Pesch, Georg Johnen and Thomas Brüning
Biomarker Insights 2010:5 95-102
Original research | Published on 22 Sep 2010



Breast Cancer Biomarker Discovery in the Functional Genomic Age: A Systematic Review of 42 Gene Expression Signatures
M.C Abba, E Lacunza, M Butti and C.M Aldaz
Biomarker Insights 2010:5 103-118
Original research | Published on 27 Oct 2010 | Highly accessed (previous month)



Validated Sandwich ELISA for the Quantification of von Willebrand Factor in Rabbit Plasma
Brendon W. Smith, Jana Strakova, Jennifer L. King, John W. Erdman Jr and William D. O’Brien Jr
Biomarker Insights 2010:5 119-127
Original research | Published on 28 Nov 2010



Biological Functions of the Genes in the Mammaprint Breast Cancer Profile Reflect the Hallmarks of Cancer
Sun Tian, Paul Roepman, Laura J van’t Veer, Rene Bernards, Femke de Snoo and Annuska M Glas
Biomarker Insights 2010:5 129-138
Original research | Published on 28 Nov 2010



Stabilizing the Code—Methods to Preserve RNA Prove Their Worth
Marc A. Williams
Biomarker Insights 2010:5 139-143
Original research | Published on 01 Dec 2010



Identification of Unique Blood and Urine Biomarkers in Influenza Virus and Staphylococcus aureus Co-infection: A Preliminary Study
Meagan A. Prescott, and Manoj K. Pastey
Biomarker Insights 2010:5 145-151
Original research | Published on 05 Dec 2010



Establishment of Prognostic Models for Astrocytic and Oligodendroglial Brain Tumors with Standardized Quantification of Marker Gene Expression and Clinical Variables
Yi-Hong Zhou, Kenneth R. Hess, Vinay R. Raj, Liping Yu, Longjian Liu, Alfred W.K. Yung and Mark E. Linskey
Biomarker Insights 2010:5 153-168
Original research | Published on 22 Dec 2010



2009:4

Gene Expression in Hair Follicle Dermal Papilla Cells after Treatment with Stanozolol
M. Reiter, M.W. Pfaffl, M. Schönfelder and H.H.D. Meyer
Biomarker Insights 2009:4 1-8
Original research | Published on 23 Dec 2008



Breath Hydrogen Gas Concentration Linked to Intestinal Gas Distribution and Malabsorption in Patients with Small-bowel Pseudo-obstruction
Yoshihisa Urita, Toshiyasu Watanabe, Tadashi Maeda, Yosuke Sasaki, Susumu Ishihara, Kazuo Hike, Masaki Sanaka, Hitoshi Nakajima and Motonobu Sugimoto
Biomarker Insights 2009:4 9-15

Original research | Published on 15 Jan 2009



Plasma Carotenoids and Biomarkers of Oxidative Stress in Patients with prior Head and Neck Cancer
Kathryn J. Hughes, Susan T. Mayne, Jeffrey B. Blumberg, Judy D. Ribaya-Mercado, Elizabeth J. Johnson and Brenda Cartmel
Biomarker Insights 2009:4 17-26
Original research | Published on 23 Mar 2009



Breath Hydrogen Produced by Ingestion of Commercial Hydrogen Water and Milk
Akito Shimouchi, Kazutoshi Nose, Makoto Yamaguchi, Hiroshi Ishiguro and Takaharu Kondo
Biomarker Insights 2009:4 27-32
Original research | Published on 09 Feb 2009



Cartilage Oligomeric Matrix Protein (COMP): A Biomarker of Arthritis
Susan Tseng, A. Hari Reddi and Paul E. Di Cesare
Biomarker Insights 2009:4 33-44
Original research | Published on 17 Feb 2009



Low Serum Alpha-1 Antitrypsin (AAT) in Family Members of Individuals with Autism Correlates with PiMZ Genotype
Anthony J. Russo, Lauren Neville and Christine Wroge
Biomarker Insights 2009:4 45-56
Original research | Published on 18 Mar 2009



Investigating Multi-cancer Biomarkers and Their Cross-predictability in the Expression Profiles of Multiple Cancer Types
George C. Tseng, Chunrong Cheng, Yan Ping Yu, Joel Nelson, George Michalopoulos and Jian-Hua Luo
Biomarker Insights 2009:4 57-79
Original research | Published on 01 May 2009



Pathway Analysis of Differentially Expressed Genes in Patients with Acute Aortic Dissection
Salah A. Mohamed, Hans H. Sievers, Thorsten Hanke, Doreen Richardt, Claudia Schmidtke, Efstratios I. Charitos, Gazanfer Belge and Joern Bullerdiek
Biomarker Insights 2009:4 81-90
Original research | Published on 06 May 2009



Changes in Plasma IL-6, Plasma VEGF and Serum YKL-40 During Treatment with Etanercept and Methotrexate or Etanercept Alone in Patients with Active Rheumatoid Arthritis Despite Methotrexate Therapy
Lene Surland Knudsen, Merete Lund Hetland, Julia Sidenius Johansen, Henrik Skjødt, Niels Daugaard Peters, Ada Colic, Karin Grau, Hans Jørgen Nielsen and Mikkel Østergaard
Biomarker Insights 2009:4 91-95
Original research | Published on 29 Sep 2009



Angiotensin II Type 1 Receptor Blockers Reduce Urinary Angiotensinogen Excretion and the Levels of Urinary Markers of Oxidative Stress and Inflammation in Patients with Type 2 Diabetic Nephropathy
Susumu Ogawa, Hiroyuki Kobori, Naro Ohashi, Maki Urushihara, Akira Nishiyama,  Takefumi Mori, Tsuneo Ishizuka, Kazuhiro Nako and Sadayoshi Ito
Biomarker Insights 2009:4 97-102
Original research | Published on 23 Jun 2009



Joint Variable Selection and Classification with Immunohistochemical Data
Debashis Ghosh and Ratna Chakrabarti
Biomarker Insights 2009:4 103-110
Original research | Published on 22 Jul 2009



Novel Biomarkers for the Diagnosis of Urinary Tract Infection - A Systematic Review
Neha Nanda and Manisha Juthani-Mehta
Biomarker Insights 2009:4 111-121
Original research | Published on 05 Aug 2009



Biomarkers of Adiponectin: Plasma Protein Variation and Genomic DNA Polymorphisms
Harvest F. Gu
Biomarker Insights 2009:4 123-133
Original research | Published on 13 Oct 2009



An Optimal Protocol to Analyze the Rat Spinal Cord Proteome
F. Gil-Dones, S. Alonso-Orgaz, G. Avila, T. Martin-Rojas, V. Moral-Darde, G. Barroso, F. Vivanco, J. Scott-Taylor and M.G. Barderas
Biomarker Insights 2009:4 135-164
Original research | Published on 28 Oct 2009



Biomarker Validation for Aging: Lessons from mtDNA Heteroplasmy Analyses in Early Cancer Detection
Peter E. Barker and Mahadev Murthy
Biomarker Insights 2009:4 165-179
Original research | Published on 27 Nov 2009



Decreased Serum Hepatocyte Growth Factor (HGF) in Autistic Children with Severe Gastrointestinal Disease
A.J. Russo, A. Krigsman, B. Jepson and Andrew Wakefield
Biomarker Insights 2009:2 181-190
Original research | Published on 27 Nov 2009



Protein Modifications as Potential Biomarkers in Breast Cancer
Hongjun Jin and Richard C. Zangar
Biomarker Insights 2009:4 191-200
Original research | Published on 30 Nov 2009



Enhanced Expression of Radiation-Induced Leukocyte CDKN1A mRNA in Multiple Primary Breast Cancer Patients: Potential New Marker of Cancer Susceptibility
Masato Mitsuhashi, David Peel, Argyrios Ziogas and Hoda Anton-Culver
Biomarker Insights 2009:4 201-209
Original research | Published on 22 Dec 2009



2008:3

Antibody Arrays Identify Potential Diagnostic Markers of Hepatocellular Carcinoma
Hongbo Sun, Mei-Sze Chua, Dorothy Yang, Anya Tsalenko, Brian J. Peter and Samuel So
Biomarker Insights 2008:3 1-18
Original research | Published on 21 Jan 2008



Marker of Bone Resorption in Acute Response to Exogenous or Endogenous Parathyroid Hormone
Vit Zikan and Jan J. Stepan
Biomarker Insights 2008:3 19-24
Original research | Published on 25 Jan 2008



Sample Stability and Protein Composition of Saliva: Implications for Its Use as a Diagnostic Fluid
Diederik Esser, Gloria Alvarez-Llamas, Marcel P. de Vries, Desiree Weening, Roel J. Vonk and Han Roelofsen
Biomarker Insights 2008:3 25-37
Original research | Published on 01 Feb 2008



Elevated CAIX Expression is Associated with an Increased Risk of Distant Failure in Early-Stage Cervical Cancer
John P. Kirkpatrick, Zahid N. Rabbani, Rex C. Bentley, Matt E. Hardee, Seth Karol, Jeffrey Meyer, Egbert Oosterwijk, Laura Havrilesky, Angeles Alvarez Secord, Zeljko Vujaskovic, Mark W. Dewhirst and Ellen L. Jones
Biomarker Insights 2008:3 45-55
Original research | Published on 01 Feb 2008



Genomic and Proteomic Biomarker Discovery in Neurological Disease
RiLee H. Robeson, Andrew M. Siegel and Travis Dunckley
Biomarker Insights 2008:3 73-86
Original research | Published on 09 Feb 2008



Candidate List of yoUr Biomarker (CLUB): A Web-based Platform to Aid Cancer Biomarker Research
Bernett T.K. Lee, Lailing Liew, Jiahao Lim, Jonathan K.L. Tan, Tze Chuen Lee, Pardha S. Veladandi, Yun Ping Lim, Hao Han, Gunaretnam Rajagopal and N. Leigh Anderson
Biomarker Insights 2008:3 65-71
Original research | Published on 09 Feb 2008



Cellular Adhesion Molecules in Healthy Subjects: Short Term Variations and Relations to Flow Mediated Dilation
Ole Eschen, Jeppe Hagstrup Christensen, Claus Dethlefsen, Erik Berg Schmidt
Biomarker Insights 2008:3 57-62
Original research | Published on 14 Feb 2008



Expression of Osteoarthritis Marker YKL-39 is Stimulated by Transforming Growth Factor Beta (TGF-beta) and IL-4 in Differentiating Macrophages
Alexei Gratchev, Christina Schmuttermaier, Srinivas Mamidi, LiMing Gooi, Sergij Goerdt and Julia Kzhyshkowska
Biomarker Insights 2008:3 39-44
Original research | Published on 14 Feb 2008



Biomarkers in Acute Kidney Injury
Jean-François Naud and Martine Leblanc
Biomarker Insights 2008:3 115-125
Original research | Published on 26 Feb 2008



Repeatedly Heading a Soccer Ball Does Not Increase Serum Levels of S-100B, a Biochemical Marker of Brain Tissue Damage: an Experimental Study
Britt-Marie Stålnacke and Peter Sojka
Biomarker Insights 2008:3 87-91
Original research | Published on 29 Feb 2008



An Evaluation of the Clinical Evidence on the Role of Inflammation and Oxidative Stress in Smoking-Mediated Cardiovascular Disease
Adam Csordas, Georg Wick, Günther Laufer and David Bernhard
Biomarker Insights 2008:3 127-139
Original research | Published on 01 Mar 2008



Serum and Ascitic Fluid Superoxide Dismutase and Malondialdehyde Levels in Patients with Cirrhosis
Seren Ozenirler, Banu Sancak and Ugur Coskun
Biomarker Insights 2008:3 141-145
Original research | Published on 12 Mar 2008



Circulating Markers Reflect Both Anti- and Pro-Atherogenic Drug Effects in ApoE-Deficient Mice
Birong Liao, Eileen McCall, Karen Cox, Chung-Wein Lee, Shuguang Huang, Richard E Higgs, Li-Chun Chio, Eugene Zhen, John E Hale, Nancy K Jackson, Pamela G Rutherford, Xiao-di Huang, Donetta Gifford-Moore, Kwan Hui, Kevin Duffin, Kenneth E Gould and Mark Rekhter
Biomarker Insights 2008:3 147-157
Original research | Published on 12 Mar 2008



Proteomic Biomarkers of Atherosclerosis
F. Vivanco, L.R. Padial, V.M. Darde, F. de la Cuesta, G. Alvarez-Llamas, Natacha Diaz-Prieto and M.G. Barderas
Biomarker Insights 2008:3 101-113
Original research | Published on 12 Mar 2008



FTIR Microspectroscopy Coupled with Two-Class Discrimination Segregates Markers Responsible for Inter- and Intra-Category Variance in Exfoliative Cervical Cytology
Michael J. Walsh, Maneesh N. Singh, Helen F. Stringfellow, Hubert M. Pollock, Azzedine Hammiche, Olaug Grude, Nigel J. Fullwood, Mark A. Pitt, Pierre L. Martin-Hirsch and Francis L. Martin
Biomarker Insights 2008:3 179-189
Original research | Published on 25 Mar 2008



The Role of Thrombospondin 1 on Intestinal Inflammation and Carcinogenesis
Linda S. Gutierrez
Biomarker Insights 2008:3 171-178
Original research | Published on 28 Mar 2008



Time Dependent Gene Expression Changes in the Liver of Mice Treated with Benzene
Han-Jin Park, Jung Hwa Oh, Seokjoo Yoon and S.V.S. Rana
Biomarker Insights 2008:3 191-201
Original research | Published on 28 Mar 2008



Chemical Biomarkers of Human Breast Milk Pollution
Francesco Massart, Giulia Gherarducci, Benedetta Marchi and Giuseppe Saggese
Biomarker Insights 2008:3 159-169
Original research | Published on 28 Mar 2008



Biomarkers of Ovarian Reserve
William E. Roudebush, Wendy J. Kivens, Jessica M. Mattke
Biomarker Insights 2008:3 259-268
Original research | Published on 16 Apr 2008



Excision Repair Cross-Complementation Group 1 Enzyme as a Molecular Determinant of Responsiveness to Platinum-Based Chemotherapy for non Small-Cell Lung Cancer
Giannis Mountzios, Meletios-Athanasios Dimopoulos and Christos Papadimitriou
Biomarker Insights 2008:3 219-226
Original research | Published on 17 Apr 2008



Dendritic Cells Promoted by Ginseng Saponins Drive a Potent Th1 Polarization
Masao Takei, Eiichi Tachikawa and Akemi Umeyama
Biomarker Insights 2008:3 269-286
Original research | Published on 18 Apr 2008



Comparison of the Calibration Standards of Three Commercially Available Multiplex Kits for Human Cytokine Measurement to WHO Standards Reveals Striking Differences
Andreas Nechansky, Susanne Grunt, Ivan M. Roitt and Ralf Kircheis
Biomarker Insights 2008:3 227-235
Original research | Published on 18 Apr 2008



Biomarkers and Bioassays for Cardiovascular Diseases: Present and Future
Derek S. Sim, Hsiao Lieu and Patrick Andre
Biomarker Insights 2008:3 293-302
Original research | Published on 19 May 2008



DICER1 and PRKRA in Colon Adenocarcinoma
S. Chiosea, M. Acquafondata, J. Luo, SF. Kuan, RR. Seethala
Biomarker Insights 2008:3 253-258
Original research | Published on 28 Apr 2008



A Rapid and Simple Bioassay Method for Herbicide Detection
Xiu-Qing Li, Alan Ng, Russell King, Dion G. Durnford
Biomarker Insights 2008:3 287-291
Original research | Published on 28 Apr 2008



What is New on Thyroid Cancer Biomarkers
Rosaria M. Ruggeri, Alfredo Campennì, Sergio Baldari, Francesco Trimarchi and Maria Trovato
Biomarker Insights 2008:3 237-252
Original research | Published on 29 Apr 2008



MUC1 as a Putative Prognostic Marker for Prostate Cancer
Rona J Strawbridge, Monica Nistér, Kerstin Brismar, Henrik Grönberg and Chunde Li
Biomarker Insights 2008:3 303-315
Original research | Published on 14 May 2008



Proteomics Discovery of Disease Biomarkers
Mamoun Ahram and Emanuel F. Petricoin
Biomarker Insights 2008:3 325-333
Original research | Published on 06 Jun 2008



Activation of Tissue Remodeling Precedes Obliterative Bronchiolitis in Lung Transplant Recipients
Allan M. Ramirez, David R. Nunley, Mauricio Rojas and Jesse Roman
Biomarker Insights 2008:3 351-359

Original research | Published on 06 Jun 2008



Tracking Differential Gene Expression in MRL/MpJ Versus C57BL/6 Anergic B Cells: Molecular Markers of Autoimmunity
Amy G. Clark, Katherine M. Mackin and Mary H. Foster
Biomarker Insights 2008:3 335-350
Original research | Published on 10 Jun 2008



Pulmonary Biomarkers of Bronchopulmonary Dysplasia
Alecia Thompson and Vineet Bhandari
Biomarker Insights 2008:3 361-373
Original research | Published on 02 Jul 2008



Detection of Colorectal Cancer by Serum and Tissue Protein Profiling: A Prospective Study in a Population at Risk
Judith Y.M.N. Engwegen, Annekatrien C.T.M. Depla, Marianne E. Smits, Annemieke Cats, Henriëtte Tuynman, Henk A. van Heukelem, Pleun Snel, Wouter Meuleman, Lodewyk Wessels, Jan H.M. Schellens and Jos H. Beijnen
Biomarker Insights 2008:3 375-385
Original research | Published on 02 Jul 2008



Hematopoietic Lineage Transcriptome Stability and Representation in PAXgeneTM Collected Peripheral Blood Utilising SPIA Single-Stranded cDNA Probes for Microarray
Laura Kennedy, J. Keith Vass, D. Ross Haggart, Steve Moore, Michael E. Burczynski, Dan Crowther and Gino Miele
Biomarker Insights 2008:3 403-417

Original research | Published on 25 Aug 2008



Usefulness of B Natriuretic Peptides and Procalcitonin in Emergency Medicine
S. Delerme, C. Chenevier-Gobeaux, B. Doumenc and P. Ray
Biomarker Insights  2008:3 203-217
Original research | Published on 27 Mar 2008



Novel Biomarkers Associated with Deep Venous Thrombosis: A Comprehensive Review
Dawn M Barnes, Thomas W Wakefield and John E Rectenwald
Biomarker Insights 2008:3 93-100
Original research | Published on 10 Apr 2008



Alzheimer’s Disease, Diagnosis and the Need for Biomarkers
Claudie Hooper, Simon Lovestone and Ricardo Sainz-Fuertes
Biomarker Insights 2008:3 317-323
Original research | Published on 27 May 2008



Effects of Cyclooxygenase Inhibitors on Apoptotic Neuroretinal Cells
Anja-Kristina Brust, Holger K. Ulbrich, Gail M. Seigel, Norbert Pfeiffer and Franz H. Grus
Biomarker Inisghts 2008:3 387-402
Original research | Published on 08 Jul 2008



Serum Concentrations of F2-Isoprostanes and 4-Hydroxynonenal in Hemodialysis Patients in Relation to Inflammation and Renal Anemia
Ingrid Wiswedel, Daniela Peter, Andreas Gardemann, Francesco Carluccio, Hannelore Hampl and Werner Siems
Biomarker Insights 2008:3 419-428
Original research | Published on 27 May 2008



Clinical Performance of a Salivary Amylase Activity Monitor During Hemodialysis Treatment
Masaru Shimazaki, Takayuki Matsuki, Kazuaki Yamauchi, Michihiro Iwata, Hiroshi Takahashi, Kenichi Sakamoto, Junichi Ohata, Yuichi Nakamura and Yusuke Okazaki
Biomarker Insights 2008:3 429-434
Original research | Published on 15 Sep 2008



Radionuclide-Based Cancer Imaging Targeting the Carcinoembryonic Antigen
Hao Hong, Jiangtao Sun and Weibo Cai
Biomarker Insights 2008:3 435-451
Original research | Published on 23 Sep 2008



Biomarkers in Acute Coronary Syndrome
Valentina Loria, Milena Leo, Gina Biasillo, Ilaria Dato and Luigi M. Biasucci
Biomarker Insights 2008:3 453-468
Original research | Published on 05 Nov 2008



2007:2

Evaluation of Cellular Fibronectin Plasma Levels as a Useful Staging Tool in Different Stages of Transitional Cell Carcinoma of the Bladder and Renal Cell Carcinoma
A. Hegele, R. Hofmann, B. Kosche and J. Kropf
Biomarker Insights 2007:2 1-7
Original research | Published on 07 Feb 2007



Clinical Significance of Telomere Length and Associated Proteins in Oral Cancer
Rachana N. Sainger, Shaila D. Telang, Shilin N. Shukla and Prabhudas S. Patel
Biomarker Insights 2007:2 9-19
Original research | Published on 14 Feb 2007



Methodology and Applications of Disease Biomarker Identification in Human Serum
Ziad J. Sahab, Suzan M. Semaan and Qing-Xiang Amy Sang
Biomarker Insights 2007:2 21-43
Original research | Published on 14 Feb 2007



Negative Regulation of Receptor Tyrosine Kinase (RTK) Signaling: A Developing Field
Fernanda Ledda and Gustavo Paratcha
Biomarker Insights 2007:2 45-58
Original research | Published on 14 Feb 2007



Microvessel Density and Clinicopathologic Characteristics in Hepatocellular Carcinoma With and Without Cirrhosis
Ivan Chebib, Meer Taher Shabani-Rad, Michelle S. Chow, James Zhang and Zu-hua Gao
Biomarker Insights 2007:2 59-68
Original research | Published on 14 Feb 2007



Leukemia Associated Antigens: Their Dual Role as Biomarkers and Immunotherapeutic Targets for Acute Myeloid Leukemia
Barbara-Ann Guinn, Azim Mohamedali, Ken I. Mills, Barbara Czepulkowski, Michael Schmitt and Jochen Greiner
Biomarker Insights 2007:2 69-79
Original research | Published on 14 Feb 2007



Pharmacodynamic Effects of an Angiotensin II Receptor-Antagonist in Phase I: Comparison between Healthy Subjects and Patients with Hypertension
Georg Wensing, Klaus Ochmann, Michael Boettcher, Anja Schäfer and Jochen Kuhlmann
Biomarker Insights 2007:2 81-93
Original research | Published on 22 Mar 2007



Biomarkers in Bladder Cancer: Present Status and Perspectives
Wun-Jae Kim, Soongang Park and Yong-June Kim
Biomarker Insights 2007:2 95-105
Original research | Published on 27 Mar 2007



Changes in Metallothionein Levels in Freshwater Mussels Exposed to Urban Wastewaters: Effects from Exposure to Heavy Metals?
F.Gagné, C.Gagnon, P.Turcotte and C.Blaise
Biomarker Insights 2007:2 107-116
Original research | Published on 29 Mar 2007



The Sample Type used Affects the Levels of Gelatinases (MMP-2 and -9) and their Inhibitors (TIMP-1 and -2) in Circulating Blood of Healthy Controls and Breast Cancer Patients
Kuvaja Paula, Talvensaari-Mattila Anne and Turpeenniemi-Hujanen Taina
Biomarker Insights 2007:2 117-127
Original research | Published on 03 Apr 2007



Human Chitinases and Chitinase-Like Proteins as Indicators for Inflammation and Cancer
Julia Kzhyshkowska, Alexei Gratchev and Sergij Goerdt
Biomarker Insights 2007:2 128-146
Original research | Published on 03 May 2007



Evaluation of Tissue Metabolites with High Resolution Magic Angle Spinning MR Spectroscopy Human Prostate Samples After Three-Year Storage at -80 ºC
Kate W. Jordan, Wenlei He, Elkan F. Halpern, Chin-Lee Wu and Leo L. Cheng
Biomarker Insights 2007:2 147-154
Original research | Published on 18 Apr 2007



Ubiquitin Fusion Degradation Protein 1 as a Blood Marker for The Early Diagnosis of Ischemic Stroke
Laure Allard, Natacha Turck, Pierre R. Burkhard, Nadia Walter, Anna Rosell, Marianne Gex-Fabry, Denis F. Hochstrasser, Joan Montaner and Jean-Charles Sanchez
Biomarker Insights 2007:2 155-164
Original research | Published on 19 Apr 2007



The Clinical Application of Anti-CCP in Rheumatoid Arthritis and Other Rheumatic Diseases
CT Chou, HT Liao, CH Chen, WS Chen, HP Wang and KY Su
Biomarker Insights 2007:2 165-171
Original research | Published on 03 May 2007



Expression of Cancer-Associated Molecules in Malignant Mesothelioma
Ben Davidson
Biomarker Insights 2007:2 173-184
Original research | Published on 30 May 2007



Biomarker Discovery in Animal Health and Disease: The Application of Post-Genomic Technologies
Rowan E. Moore, Jennifer Kirwan, Mary K. Doherty and Phillip D. Whitfield
Biomarker Insights 2007:2 185-196
Original research | Published on 10 Jul 2007



Molecular Markers for Biomass Traits: Association, Interaction and Genetic Divergence in Silkworm Bombyx mori
Appukuttannair R Pradeep, Anuradha H Jingade and Raje S Urs
Biomarker Insights 2007:2 197-217
Original research | Published on 30 May 2007



Protein Tyrosine Phosphatase Gamma (PTPγ) is a Novel Leukocyte Marker Highly Expressed by CD34+ Precursors
Andrea Mafficini, Marzia Vezzalini, Loris Zamai, Laura Galeotti, Gabriella Bergamini, Marco Della Peruta, Paola Melotti and Claudio Sorio
Biomarker Insights 2007:2 218-225
Original research | Published on 31 May 2007



TLR2 and TLR4 as Potential Biomarkers of Environmental Particulate Matter Exposed Human Myeloid Dendritic Cells
Marc A. Williams, Chris Cheadle, Tonya Watkins, Anitaben Tailor, Smruti Killedar, Patrick Breysse, Kathleen C. Barnes and Steve N. Georas
Biomarker Insights 2007:2 226-240
Original research | Published on 30 May 2007



Mouse Germ Cell Development in-vivo and in-vitro
Deshira Saiti and Orly Lacham-Kaplan
Biomarker Insights 2007:2 241-252
Original research | Published on 06 Jun 2007



Gene Expression Profiles from Needle Biopsies Provide Useful Signatures of Non-Small Cell Lung Carcinomas
Douglas E. Paull, Kevin Kelley, Jazbieh Moezzi, Madhavi Kadakia, and Steven J. Berberich
Biomarker Insights 2007:2 253-259
Original research | Published on 08 Jun 2007



Multianalyte Tests for the Early Detection of Cancer: Speedbumps and Barriers
Michael A. Tainsky, Madhumita Chatterjee, Nancy K. Levin, Sorin Draghici and Judith Abrams
Biomarker Insights 2007:2 261-267
Original research | Published on 10 Jul 2007



Determination of Tobacco Specific Hemoglobin Adducts in Smoking Mothers and New Born Babies by Mass Spectrometry
Steven R. Myers and Md. Yeakub Ali
Biomarker Insights 2007:2 269-282
Original research | Published on 06 Aug 2007



Genome-Wide Association Studies: Progress in Identifying Genetic Biomarkers in Common, Complex Diseases
Stephen F. Kingsmore, Ingrid E. Lindquist, Joann Mudge and William D. Beavis
Biomarker Insights 2007:2 283-292
Original research | Published on 08 Aug 2007



Studies of Wilms’ Tumor (WT1) Gene Expression in Adult Acute Leukemias in Singapore
Che Kang Lim, Yeow Tee Goh, William Y. K. Hwang, Liam Pock Ho and Li Sun
Biomarker Insights 2007:2 293-298
Original research | Published on 08 Aug 2007



Alteration of Transthyretin Microheterogeneity in Serum of Multiple Trauma Patients
Beate Gericke, Jens Raila, Maria Deja, Sascha Rohn, Bernd Donaubauer, Britta Nagl, Sophie Haebel, Florian J. Schweigert and Udo Kaisers
Biomarker Insights 2007:2 299-306
Original research | Published on 08 Aug 2007



DNA Methylation in Circulating Tumour DNA as a Biomarker for Cancer
Ruth E Board, Lucy Knight, Alastair Greystoke, Fiona H Blackhall, Andrew Hughes, Caroline Dive and Malcolm Ranson
Biomarker Insights 2007:2 307-319
Original research | Published on 25 Jan 2008



Electron Pathways through Erythrocyte Plasma Membrane in Human Physiology and Pathology: Potential Redox Biomarker?
Elena Matteucci and Ottavio Giampietro
Biomarker Insights 2007:2 321-329
Original research | Published on 17 Sep 2007



Endogenous Secretory RAGE as a Novel Biomarker for Metabolic Syndrome and Cardiovascular Diseases
Hidenori Koyama, Hiroshi Yamamoto and Yoshiki Nishizawa
Biomarker Insights 2007:2 331-339
Original research | Published on 17 Sep 2007



Recursive Partitioning Analysis of Mediastinal N2 Lymph Node Involvement with Selected Biological Markers in Operable Non-small Cell Lung Cancer: A Correlative Study
Hakan Bozcuk, Aziz Gumus, Gulay Ozbilim, Alpay Sarper, Kucukosmanoglu Ilknur, Mustafa Ozdogan and Abit Demircan
Biomarker Insights 2007:2 341-346
Original research | Published on 06 Oct 2007



Proteomics and Mass Spectrometry for Cancer Biomarker Discovery
Ming Lu, Kym F. Faull, Julian P. Whitelegge, Jianbo He, Dejun Shen, Romaine E. Saxton and Helena R. Chang
Biomarker Insights 2007:2 347-360
Original research | Published on 03 Oct 2007



Changes in Hyaluronan Metabolism and RHAMM Receptor Expression Accompany Formation of Complicated Carotid Lesions and May be Pro-Angiogenic Mediators of Intimal Neovessel Growth
Jerzy Krupinski, Priya Ethirajan, M. Angels Font, Marta Miguel Turu, John Gaffney, Pat Kumar and Mark Slevin
Biomarker Insights 2007:2 361-367
Original research | Published on 12 May 2008



Validation of Candidate Serum Ovarian Cancer Biomarkers for Early Detection
Feng Su, Jennifer Lang, Ashutosh Kumar, Carey Ng, Brian Hsieh, Marc A. Suchard, Srinivasa T. Reddy, Robin Farias-Eisner
Biomarker Insights 2007:2 369-375
Original research | Published on 16 Oct 2007



Induction of Proteases in Peritoneal Carcinomatosis, the Role of ICAM-1/CD43 Interaction
Nawar A. Alkhamesi, Gretta Roberts, Paul Ziprin and David H. Peck
Biomarker Insights 2007:2 377-384
Original research | Published on 08 Oct 2007



Endogenous Plasma Peptide Detection and Identification in the Rat by a Combination of Fractionation Methods and Mass Spectrometry
Fabrice Bertile, Flavie Robert, Véronique Delval-Dubois, Sarah Sanglier, Christine Schaeffer and Alain Van Dorsselaer
Biomarker Insights 2007:2 385-401
Original research | Published on 09 Oct 2007



Prognostic Significance of in situ Phenotypic Marker Expression in Diffuse Large B-cell Lymphomas
Alexandar Tzankov, Philip Went and Stephan Dirnhofer
Biomarker Insights 2007:2 403-417
Original research | Published on 11 Nov 2007



The Role of Structural Extracellular Matrix Proteins in Urothelial Bladder Cancer
Andrea Brunner and Alexandar Tzankov
Biomarker Insights 2007:2 418-427
Original research | Published on 05 Nov 2007



Clastogenic Factors as Potential Biomarkers of Increased Superoxide Production
Ingrid Emerit
Biomarker Insights 2007:2 429-438
Original research | Published on 11 Dec 2007



Genetic Alterations in Pesticide Exposed Bolivian Farmers: An evaluation by analysis of chromosomal aberrations and the comet assay
Erik Jørs, Ana Rosa Gonzáles, Maria Eugenia Ascarrunz, Noemi Tirado, Catharina Takahashi, Erika Lafuente, Raquel A Dos Santos, Natalia Bailon, Rafael Cervantes, Huici O, Jesper Bælum, Flemming Lander
Biomarker Insights 2007:2 439-445
Original research | Published on 12 Nov 2007



Using LongSAGE to Detect Biomarkers of Cervical Cancer Potentially Amenable to Optical Contrast Agent Labelling
Julie M. Kneller, Thomas Ehlen, Jasenka P. Matisic, Dianne Miller, Dirk Van Niekerk, Wan L. Lam, Marco Marra, Rebecca Richards-Kortum, Michelle Follen, Calum MacAulay and Steven J.M. Jones
Biomarker Insights 2007:2 447-461
Original research | Published on 11 Dec 2007



Increased Intrathecal Chemokine Receptor CCR2 Expression in Multiple Sclerosis
Hideto Nakajima, Masakazu Sugino, Fumiharu Kimura, Toshiaki Hanafusa,Toshiyuki Ikemoto and Akira Shimizu
Biomarker Insights 2007:2 463-468
Original research | Published on 18 Dec 2007



An EGFR and AKT Signaling Pathway was Identified with Mediation Model in Osteosarcomas Clinical Study
Huiyun Wu, Nicole E. Muscato, Adriana Gonzalez and Yu Shyr
Biomarker Insights 2007:2 469-476
Original research | Published on 11 Dec 2007



2006:1

A List of Candidate Cancer Biomarkers for Targeted Proteomics
Malu Polanski and N. Leigh Anderson
Biomarker Insights 2006:1 1-48
Original research | Published on 07 Feb 2007



BRCA1 Expression is an Important Biomarker for Chemosensitivity: Suppression of BRCA1 Increases the Apoptosis via Up-regulation of p53 and p21 During Cisplatin Treatment in Ovarian Cancer Cells
Akiko Horiuchi, Cuiju Wang, Norihiko Kikuchi, Ryosuke Osada, Toshio Nikaido and Ikuo Konishi
Biomarker Insights 2006:1 49-59
Original research | Published on 02 Mar 2007



Collagen Biomarkers for Arthritis Applications
James D. Birmingham, Vladimir Vilim and Virginia B. Kraus
Biomarker Insights 2006:1 61-76
Original research | Published on 07 Feb 2007



Serum C-Reactive Protein (CRP), Target for Therapy or Trouble?
Virginia B. Kraus and Joanne M. Jordan
Biomarker Insights 2006:1 77-80
Original research | Published on 07 Feb 2007



Alpha-Fetoprotein: From a Diagnostic Biomarker to a Key Role in Female Fertility
Christelle De Mees, Julie Bakker, Josiane Szpirer and Claude Szpirer
Biomarker Insights 2006:1 82-85
Original research | Published on 07 Feb 2007



C-reactive Protein in Patients with Metastatic Clear Cell Renal Carcinoma: An Important Biomarker for Tumor-associated Inflammation
Albrecht Reichle, Jochen Grassinger, Klaus Bross, Jochen Wilke, Thomas Suedhoff, Bernhard Walter, Wolf-Ferdinand Wieland, Anna Berand and Reinhard Andreesen
Biomarker Insights 2006:1 87-98
Original research | Published on 07 Feb 2007



The Balance between Life and Death of Cells: Roles of Metallothioneins
Allan Evald Nielsen, Adam Bohr and Milena Penkowa
Biomarker Insights 2006:1 99-111
Original research | Published on 07 Feb 2007



Prognostic Values of microRNAs in Colorectal Cancer
Yaguang Xi, Andrea Formentini, Minchen Chien, David B. Weir, James J. Russo, Jingyue Ju, Marko Kornmann and Jingfang Ju
Biomarker Insights 2006:1 113-121
Original research | Published on 07 Feb 2007



Acute Coronary Syndromes: From The Laboratory Markers To The Coronary Vessels
Palazzuoli Alberto, Iovine Francesca, Scali Chiara and Nuti Ranuccio
Biomarker Insights 2006:1 123-130
Original research | Published on 07 Feb 2007



Do We Need Biomarkers for Disc Degeneration?
Helen E. Gruber and Edward N. Hanley, Jr.
Biomarker Insights 2006:1 131-133
Original research | Published on 07 Feb 2007



Gastric Cancer (Biomarkers) Knowledgebase (GCBKB): A Curated and Fully Integrated Knowledgebase of Putative Biomarkers Related to Gastric Cancer
Bernett T.K. Lee, Chun Meng Song, Boon Huat Yeo, Cheuk Wang Chung, Ying Leong Chan, Teng Ting Lim, Yen Bing Chua, Marie C.S. Loh, Boon Keong Ang, Praveen Vijayakumar, Lailing Liew, Jiahao Lim, Yun Ping Lim, Chee Hong Wong, Danny Chuon, Gunaretnam Rajagopal and Jeffrey Hill
Biomarker Insights 2006:1 135-141
Original research | Published on 07 Feb 2007



The Importance of Amino-terminal pro-Brain Natriuretic Peptide Testing in Clinical Cardiology
R. R. J. van Kimmenade and J. L. Januzzi Jr
Biomarker Insights 2006:1 143-155
Original research | Published on 07 Feb 2007



Study of the Urinary Ratio of 6 ß-Hydroxycortisol/Cortisol as a Biomarker of CYP3A4 Activity in Egyptian Patients with Chronic Liver Diseases
Ehab S. El Desoky, Sherif I. Kamel, Ahlam M. Farghaly, Madiha Y. Bakheet, Mohsen A. Hedaya and Jean-Pascal Siest
Biomarker Insights 2006:1 157-164
Original research | Published on 07 Feb 2007



Integrating Soluble Biomarkers and Imaging Technologies in the Identification of Vulnerable Atherosclerotic Patients
José A. Páramo, José A. Rodríguez JA, and Josune Orbe
Biomarker Insights 2006:1 165-173
Original research | Published on 07 Feb 2007



Identification of a specific Vimentin Isoform that induces an antibody response in pancreatic cancer
Su-Hyung Hong, David E. Misek, Hong Wang, Eric Puravs, Robert Hinderer, Thomas J. Giordano, Joel K. Greenson, Dean E. Brenner, Diane M. Simeone, Craig D. Logsdon and Samir M. Hanash
Biomarker Insights 2006:1 175-183
Original research | Published on 07 Feb 2007



Serum Lipid Profile Constituents as Markers of Cardio-vascular Morbidity in Patients on Chronic Hemodialysis
Dimitrios Kirmizis, Evangelia Koutoupa, Apostolos Tsiandoulas, Aphroditi Valtopoulou, Georgios Niavis, Phani Markou and Konstantinos Barboutis
Biomarker Insights 2006:1 185-192
Original research | Published on 07 Feb 2007



Comparison of Apoptosis Detection Markers Combined with Macrophage Immunostaining to Study Phagocytosis of Apoptotic Cells in Situ
Dorien M. Schrijvers, Guido R.Y. De Meyer, Mark M. Kockx, Arnold G. Herman and Wim Martinet
Biomarker Insights 2006:1 193-200
Original research | Published on 07 Feb 2007



Soluble CD26 is inversely Associated with Disease Severity in Patients with Chronic Eosinophilic Pneumonia
Osamu Matsuno, Eishi Miyazaki, Shinichi Nureki, Takuya Ueno, Masaru Ando and Toshihide Kumamoto
Biomarker Insights 2006:1 201-204
Original research | Published on 07 Feb 2007



Ceruloplasmin (2-D PAGE) Pattern and Copper Content in Serum and Brain of Alzheimer Disease Patients
Rosanna Squitti, Carlo C. Quattrocchi, Gloria Dal Forno, Piero Antuono, David R. Wekstein, Concetta R. Capo, Carlo Salustri and Paolo M. Rossini
Biomarker Insights 2006:1 205-213
Original research | Published on 07 Feb 2007



Biomarkers in Cervical Cancer
Eun-Kyoung Yim and Jong-Sup Park
Biomarker Insights 2006:1 215-225
Original research | Published on 07 Feb 2007





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