Close
Help





JOURNAL

Environmental Health Insights

Plasma Cholinesterase Levels of Nepalese Farmers Following Exposure to Organophosphate Pesticides

Submit a Paper


Environmental Health Insights 2017:11 1178630217719269

Review

Published on 10 Jul 2017

DOI: 10.1177/1178630217719269


Further metadata provided in PDF



Sign up for email alerts to receive notifications of new articles published in Environmental Health Insights

Abstract

Background:

Farmers in developing countries use highly toxic organophosphate pesticides. Thus, the aim of this study was to compare plasma cholinesterase (PChE) enzyme activity before and after exposure to organophosphate pesticides in a real-life setting.

Methods:

This was a prospective study conducted on 25 farmers spraying organophosphate pesticide in their farm. The PChE level was measured and clinical signs and symptoms of toxicity were asked before and immediately after spraying.

Results:

The mean level of PChE before and after spraying was 1.41 and 1.29 IU/L, respectively (8.51% decreased). Farmers reported more clinical signs and symptoms of intoxication after spraying pesticides.

Conclusions:

Increase in acute intoxication signs/symptoms and decrease in PChE indicate a serious public health problem among farmers who use organophosphate pesticides. Appropriate training to the farmers is needed to reduce exposure to organophosphate pesticide.



Downloads

PDF  (461.34 KB PDF FORMAT)

RIS citation   (ENDNOTE, REFERENCE MANAGER, PROCITE, REFWORKS)

XML   (34.32 KB XML FORMAT)

BibTex citation   (BIBDESK, LATEX)





Quick Links


New article and journal news notification services