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Clinical Medicine Insights: Oncology

Targeted Therapies in the Treatment of Advanced Hepatocellular Carcinoma

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Clinical Medicine Insights: Oncology 2013:7 87-102

Review

Published on 20 May 2013

DOI: 10.4137/CMO.S7633


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The Editor-in-Chief has endorsed this article

A nice review on a very important topic.

Abstract

Hepatocellular carcinoma (HCC) is the most common liver cancer and the third leading cause of cancer death. It has been a major worldwide health problem with more new cases being diagnosed each year. The current available therapies for patients with advanced HCC are extremely limited. Therefore, it is of great clinical interests to develop more effective therapies for systemic treatment of advanced HCC. Several promising target-based drugs have been tested in a number of clinical trials. One breakthrough of these efforts is the approved clinical use of sorafenib in patients with advanced HCC. Targeted therapies are becoming an attractive option for the treatment of advanced HCC. In this review, we summarize the most recent progress in clinical targeted treatments of advanced HCC.



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