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Biomarkers in Cancer

The Present and Future of Biomarkers in Prostate Cancer: Proteomics, Genomics, and Immunology Advancements

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Biomarkers in Cancer 2016:Suppl. 2 15-33

Review

Published on 05 May 2016

DOI: 10.4137/BIC.S31802


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Abstract

Prostate cancer (PC) is the second most common form of cancer in men worldwide. Biomarkers have emerged as essential tools for treatment and assessment since the variability of disease behavior, the cost and diversity of treatments, and the related impairment of quality of life have given rise to a need for a personalized approach. High-throughput technology platforms in proteomics and genomics have accelerated the development of biomarkers. Furthermore, recent successes of several new agents in PC, including immunotherapy, have stimulated the search for predictors of response and resistance and have improved the understanding of the biological mechanisms at work. This review provides an overview of currently established biomarkers in PC, as well as a selection of the most promising biomarkers within these particular fields of development.



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What Your Colleagues Say About Biomarkers in Cancer
Biomarkers in Cancer, was again a pleasant experience.  We received helpful suggestions from the reviewers and an efficient, very professional editing processing process afterwards. Excellent team-work!  We hope for the same quantity of reads/citations as for our previous publication in Clinical Medicine Insights: Oncology.
Dr Cornelis F.M. Sier (Leiden University Medical Center, Netherlands)
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