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Clinical Medicine Insights: Oncology

Transbronchial Dissemination of Squamous Cell Lung Cancer

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Clinical Medicine Insights: Oncology 2015:9 129-133

Case report

Published on 08 Dec 2015

DOI: 10.4137/CMO.S32707


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Abstract

We report a case of squamous cell lung cancer with transbronchial dissemination in a 73-year-old man. Bronchoscopic examination revealed multiple bronchial mucosal nodules that existed independently of one another. We reviewed 16 previous cases of endobronchial metastasis in lung cancer. All patients were men. Among the reports that described the smoking history, most patients were smokers (6/7), and the most frequent histological type of cancer was squamous cell carcinoma (11/17). Although hematogenous and lymphogenous routes have been reported as metastatic mechanisms, no previous cases involving transbronchial dissemination have been described. Transbronchial dissemination may be an alternative pathway of endobronchial metastasis.



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