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Japanese Clinical Medicine

Treatment of Myasthenia Gravis in Patients with Elderly Onset at Advanced Age

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Japanese Clinical Medicine 2015:6 9-13

Case report

Published on 23 Jul 2015

DOI: 10.4137/JCM.S29601


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Abstract

The number of patients with late-onset myasthenia gravis (MG) among patients ≥ 50 years has been increasing recently. We encountered three patients who developed elderly-onset MG at a particularly advanced age (≥ 80 years). All were female and positive for anti-acetylcholine receptor antibodies. About 4 years have passed since MG onset in all three patients and symptoms have been controlled without recurrence using a combination of oral low-dose prednisolone and tacrolimus. As many cases of elderly-onset MG do not require strong immunosuppression, we recommend minimum immunosuppressive treatment to avoid adverse events, particularly in patients at an advanced age of ≥ 80 years.



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