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JOURNAL

Cancer Informatics


An international, peer reviewed, open access journal that focuses on reporting bioinformatic analysis of molecular genetic and/or clinical data pertaining to human cancer risk, prevention, outcome or treatment response.  The journal recognizes that scientific collaborations across traditional disciplines can yield exponential synergistic gains: cancer research benefits from advances in many fields, including genomics and proteomics, mass spectrometry and radio imaging, computer science and biostatistics including machine learning and artificial intelligence, and medical informatics. The journal also recognizes the centrality of computational biology in these synergies.

Editor in Chief: Dr. J. T. Efird

ISSN: 1176-9351

Processing Speed: High quality, constructive peer review and rapid editorial decision within an average of four weeks.



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Article Search

Quantitative Study of Thermal Disturbances Due to Nonuniformly Perfused Tumors in Peripheral Regions of Women’s Breast
Akshara Makrariya, Neeru Adlakha
Cancer Informatics 2017:16 1176935117700894
Original Research | Published on 15 May 2017



Time-Based Switching Control of Genetic Regulatory Networks: Toward Sequential Drug Intake for Cancer Therapy
Wasiu Opeyemi Oduola, Xiangfang Li, Chang Duan, Lijun Qian, Fen Wu, Edward R Dougherty
Cancer Informatics 2017:16 1176935117706888
Review | Published on 10 May 2017



Applying Multivariate Adaptive Splines to Identify Genes With Expressions Varying After Diagnosis in Microarray Experiments
Fenghai Duan, Ye Xu
Cancer Informatics 2017:16 1176935117705381
Review | Published on 04 May 2017



miR-10a and miR-204 as a Potential Prognostic Indicator in Low-Grade Gliomas
Ju Cheol Son, Hyoung Oh Jeong, Deaui Park, Sang Gyoon No, Eun Kyeong Lee, Jaewon Lee, Hae Young Chung
Cancer Informatics 2017:16 1176935117702878
Original Research | Published on 12 Apr 2017



A mixture copula Bayesian network model for multimodal genomic data
Qingyang Zhang, Xuan Shi
Cancer Informatics 2017:16 1176935117702389
Methodology | Published on 12 Apr 2017



Bioinformatics Education in Pathology Training: Current Scope and Future Direction
Michael R Clay, Kevin E Fisher
Cancer Informatics 2017:16 1176935117703389
Review | Published on 10 Apr 2017



Therapeutic Interventions of Cancers Using Intrinsically Disordered Proteins as Drug Targets: c-Myc as Model System
Deepak Kumar, Nitin Sharma, Rajanish Giri
Cancer Informatics 2017:16 1176935117699408
Review | Published on 16 Mar 2017



Roadmap to a Comprehensive Clinical Data Warehouse for Precision Medicine Applications in Oncology
David J Foran, Wenjin Chen, Huiqi Chu, Evita Sadimin, Doreen Loh, Gregory Riedlinger, Lauri A Goodell, Shridar Ganesan, Kim Hirshfield, Lorna Rodriguez, Robert S DiPaola
Cancer Informatics 2017:16 1176935117694349
Original Research | Published on 02 Mar 2017



Integrative Analysis of Gene Networks and Their Application to Lung Adenocarcinoma Studies
Sangin Lee, Faming Liang, Ling Cai, Guanghua Xiao
Cancer Informatics 2017:16 1176935117690778
Original Research | Published on 23 Feb 2017



Significant Prognostic Features and Patterns of Somatic Mutations in Human Cancers
Wensheng Zhang, Andrea Edwards, Erik K Flemington, Kun Zhang
Cancer Informatics 2017:16 1176935117691267
Original Research | Published on 20 Feb 2017



Improving Gastric Cancer Outcome Prediction Using Single Time-Point Artificial Neural Network Models
Hamid Nilsaz-Dezfouli, Mohd Rizam Abu-Bakar, Jayanthi Arasan, Mohd Bakri Adam, Mohamad Amin Pourhoseingholi
Cancer Informatics 2017:16 1176935116686062
Original Research | Published on 16 Feb 2017



A Numerical Handling of the Boundary Conditions Imposed by the Skull on an Inhomogeneous Diffusion-Reaction Model of Glioblastoma Invasion Into the Brain: Clinical Validation Aspects
Georgios S Stamatakos, Stavroula G Giatili
Cancer Informatics 2017:16 1176935116684824
Original Research | Published on 03 Feb 2017



Epithelial Ovarian Cancer Diagnosis of Second-Harmonic Generation Images: A Semiautomatic Collagen Fibers Quantification Protocol
Angel A Zeitoune, Johana SJ Luna, Kynthia Sanchez Salas, Luciana Erbes, Carlos L Cesar, Liliana ALA Andrade, Hernades F Carvahlo, Fátima Bottcher-Luiz, Victor H Casco, Javier Adur
Cancer Informatics 2017:16 1176935117690162
Original Research | Published on 03 Feb 2017



Unified Least Squares Methods for the Evaluation of Diagnostic Tests With the Gold Standard
Liansheng Larry Tang, Ao Yuan, John Collins, Xuan Che, Leighton Chan
Cancer Informatics 2017:16 1176935116686063
Review | Published on 03 Feb 2017



Bayesian ABC-MCMC Classification of Liquid Chromatography–Mass Spectrometry Data
Upamanyu Banerjee and Ulisses M. Braga-Neto
Cancer Informatics 2015:Suppl. 5 175-182
Methodology | Published on 09 Jan 2017



Identification of Genetic and Epigenetic Variants Associated with Breast Cancer Prognosis by Integrative Bioinformatics Analysis
Arunima Shilpi, Yingtao Bi, Segun Jung, Samir K. Patra and Ramana V. Davuluri
Cancer Informatics 2017:16 1-13
Original Research | Published on 09 Jan 2017



A Novel Optical Bioimaging Method for Direct Assessment of Ovarian Cancer Chemotherapy Response at Laparoscopy
Alexandros Laios, Davide Volpi, Rajeev Kumar, Zoe Traill, Borivoj Vojnovic and Ahmed A. Ahmed
Cancer Informatics 2016:15 243-245
Short Report | Published on 08 Jan 2017



ROC Estimation from Clustered Data with an Application to Liver Cancer Data
Joungyoun Kim, Sung-Cheol Yun, Johan Lim, Moo-Song Lee, Won Son and DoHwan Park
Cancer Informatics 2016:Suppl. 4 19-26
Original Research | Published on 22 Dec 2016



Quantitative Proteomic Approach for MicroRNA Target Prediction Based on 18O/16O Labeling
Xuepo Ma, Ying Zhu, Yufei Huang, Tony Tegeler, Shou-Jiang Gao and Jianqiu Zhang
Cancer Informatics 2015:Suppl. 5 163-173
Original Research | Published on 08 Dec 2016



Comparison of Three Information Sources for Smoking Information in Electronic Health Records
Liwei Wang, Xiaoyang Ruan, Ping Yang and Hongfang Liu
Cancer Informatics 2016:15 237-242
Original Research | Published on 08 Dec 2016



A Modular Repository-based Infrastructure for Simulation Model Storage and Execution Support in the Context of In Silico Oncology and In Silico Medicine
Nikolaos A. Christodoulou, Nikolaos E. Tousert, Eleni Ch. Georgiadi, Katerina D. Argyri, Fay D. Misichroni and Georgios S. Stamatakos
Cancer Informatics 2016:15 219-235
Original Research | Published on 27 Oct 2016



Discovering Outliers of Potential Drug Toxicities Using a Large-scale Data-driven Approach
Jake Luo and Ron A. Cisler
Cancer Informatics 2016:15 211-217
Original Research | Published on 26 Oct 2016



Cluster Analysis of p53 Binding Site Sequences Reveals Subsets with Different Functions
Ji-Hyun Lim, Natasha S. Latysheva, Richard D. Iggo, and Daniel Barker
Cancer Informatics 2016:15 199-209
Original Research | Published on 25 Oct 2016



A Novel Graph-based Algorithm to Infer Recurrent Copy Number Variations in Cancer
Chen Chi, Rasif Ajwad, Qin Kuang and Pingzhao Hu
Cancer Informatics 2016:Suppl. 2 43-50
Methodology | Published on 09 Oct 2016



Discovering MicroRNA-Regulatory Modules in Multi-Dimensional Cancer Genomic Data: A Survey of Computational Methods
Christopher J. Walsh, Pingzhao Hu, Jane Batt, and Claudia C. dos Santos
Cancer Informatics 2016:Suppl. 2 25-42
Review | Published on 03 Oct 2016



Novel Biomarker Candidates for Colorectal Cancer Metastasis: A Meta-analysis of In Vitro Studies
Nguyen Phuoc Long, Wun Jun Lee, Nguyen Truong Huy, Seul Ji Lee, Jeong Hill Park and Sung Won Kwon
Cancer Informatics 2016:Suppl. 4 11-17
Original Research | Published on 22 Sep 2016



Identifying Significant Features in Cancer Methylation Data Using Gene Pathway Segmentation
Zena M. Hira and Duncan F. Gillies
Cancer Informatics 2016:15 189-198
Methodology | Published on 20 Sep 2016



Overlapping Group Logistic Regression with Applications to Genetic Pathway Selection
Yaohui Zeng and Patrick Breheny
Cancer Informatics 2016:15 179-187
Methodology | Published on 15 Sep 2016



DNA Methylation Heterogeneity Patterns in Breast Cancer Cell Lines
Sunny Tian, Karina Bertelsmann, Linda Yu and Shuying Sun
Cancer Informatics 2016:Suppl. 4 1-9
Original Research | Published on 07 Sep 2016



Biological Networks for Cancer Candidate Biomarkers Discovery
Wenying Yan, Wenjin Xue, Jiajia Chen and Guang Hu
Cancer Informatics 2016:Suppl. 3 1-7
Review | Published on 04 Sep 2016



Characterization of Gene Expression Patterns among Artificially Developed Cancer Stem Cells Using Spherical Self-Organizing Map
Akimasa Seno, Tomonari Kasai, Masashi Ikeda, Arun Vaidyanath, Junko Masuda, Akifumi Mizutani, Hiroshi Murakami, Tetsuya Ishikawa and Masaharu Seno
Cancer Informatics 2016:15 163-178
Original Research | Published on 16 Aug 2016



ExSurv: A Web Resource for Prognostic Analyses of Exons Across Human Cancers Using Clinical Transcriptomes
Seyedsasan Hashemikhabir, Gungor Budak and Sarath Chandra Janga
Cancer Informatics 2016:Suppl. 2 17-24
Technical Advance | Published on 07 Aug 2016 | Video abstract



Pathway-Informed Classification System (PICS) for Cancer Analysis Using Gene Expression Data
Michael R Young, and David L Craft
Cancer Informatics 2016:15 151-161
Original Research | Published on 27 Jul 2016



Recursive Partitioning Method on Competing Risk Outcomes
Wei Xu, Jiahua Che, and Qin Kong
Cancer Informatics 2016:Suppl. 2 9-16
Methodology | Published on 26 Jul 2016



Normalized lmQCM: An Algorithm for Detecting Weak Quasi-Cliques in Weighted Graph with Applications in Gene Co-Expression Module Discovery in Cancers
Jie Zhang and Kun Huang
Cancer Informatics 2014:Suppl. 3 137-146
Original Research | Published on 24 Jul 2016



TMAinspiration: Decode Interdependencies in Multifactorial Tissue Microarray Data
Florian Boecker, Horst Buerger, Nikhil V. Mallela and Eberhard Korsching
Cancer Informatics 2016:15 143-149
Methodology | Published on 29 Jun 2016



An Integrated Approach for RNA-seq Data Normalization
Shengping Yang, Donald E. Mercante, Kun Zhang and Zhide Fang
Cancer Informatics 2016:15 129-141
Original Research | Published on 27 Jun 2016



The Melanoma MAICare Framework: A Microsimulation Model for the Assessment of Individualized Cancer Care
Elisabeth van der Meijde, Alfons J. M. van den Eertwegh, Sabine C. Linn, Gerrit A. Meijer, Remond J. A. Fijneman, and Veerle M. H. Coupé
Cancer Informatics 2016:15 115-127
Original Research | Published on 15 Jun 2016



multiClust: An R-package for Identifying Biologically Relevant Clusters in Cancer Transcriptome Profiles
Nathan Lawlor, Alec Fabbri, Peiyong Guan, Joshy George and R. Krishna Murthy Karuturi
Cancer Informatics 2016:15 103-114
Software or Database Review | Published on 12 Jun 2016



A Novel Approach to Predict Core Residues on Cancer-Related DNA-Binding Domains
Ka-Chun Wong
Cancer Informatics 2016:Suppl. 2 1-7
Original Research | Published on 02 Jun 2016



Rational Design of Peptide Vaccines Against Multiple Types of Human Papillomavirus
Sumanta Dey, Antara De and Ashesh Nandy
Cancer Informatics 2016:Suppl. 1 1-16
Original Research | Published on 01 Jun 2016 | Video abstract



A Bayesian Nonparametric Approach for Functional Data Classification with Application to Hepatic Tissue Characterization
Kassandra M. Fronczyk, Michele Guindani, Brian P. Hobbs, Chaan S. Ng and Marina Vannucci
Cancer Informatics 2015:Suppl. 5 151-162
Original Research | Published on 29 May 2016



Bioinformatic Studies to Predict MicroRNAs with the Potential of Uncoupling RECK Expression from Epithelial–Mesenchymal Transition in Cancer Cells
Zhipeng Wang, Ryusuke Murakami, Kanako Yuki, Yoko Yoshida and Makoto Noda
Cancer Informatics 2016:15 91-102
Original Research | Published on 19 May 2016



Selecting Reliable mRNA Expression Measurements Across Platforms Improves Downstream Analysis
Pan Tong, Lixia Diao, Li Shen, Lerong Li, John Victor Heymach, Luc Girard, John D. Minna, Kevin R. Coombes, Lauren Averett Byers and Jing Wang
Cancer Informatics 2016:15 81-89
Original Research | Published on 10 May 2016



Thyroid Cancer and Tumor Collaborative Registry (TCCR)
Oleg Shats, Whitney Goldner, Jianmin Feng, Alexander Sherman, Russell B. Smith and Simon Sherman
Cancer Informatics 2016:15 73-79
Technical Advance | Published on 03 May 2016



A New Approach for Identification of Cancer-related Pathways using Protein Networks and Genomic Data
André Fonseca, Marco D. Gubitoso, Marcelo S. Reis, Sandro J. de Souza, and Junior Barrera
Cancer Informatics 2015:Suppl. 5 139-149
Original Research | Published on 02 May 2016



RefCNV: Identification of Gene-Based Copy Number Variants Using Whole Exome Sequencing
Lun-Ching Chang, Biswajit Das, Chih-Jian Lih, Han Si, Corinne E. Camalier, Paul M. McGregor III and Eric Polley
Cancer Informatics 2016:15 65-71
Methodology | Published on 27 Apr 2016



Immunomediated Pan-cancer Regulation Networks are Dominant Fingerprints After Treatment of Cell Lines with Demethylation
Mariama El Baroudi, Caterina Cinti and Enrico Capobianco
Cancer Informatics 2016:15 45-64
Original Research | Published on 27 Apr 2016



Data Requirements for Model-Based Cancer Prognosis Prediction
Lori A. Dalton and Mohammadmahdi R. Yousefi
Cancer Informatics 2015:Suppl. 5 123-138
Original Research | Published on 21 Apr 2016



High-Dimensional Statistical Learning: Roots, Justifications, and Potential Machineries
Amin Zollanvari
Cancer Informatics 2015:Suppl. 5 109-121
Review | Published on 12 Apr 2016





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