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Biomarker Insights

Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge

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Biomarker Insights 2017:12 1177271917695237

Case report

Published on 16 Mar 2017

DOI: 10.1177/1177271917695237


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Abstract

Leptomeningeal carcinomatosis (LC) is a rare and mainly secondary site of metastasis in solid tumors. In gastric cancer (GC), it is associated with a devastating prognosis, lacking an efficient and standardized treatment approach. We report a case of primary manifestation of LC due to metastatic GC with rapid deterioration and refractory course to conventional and intrathecal chemotherapy. We review the literature and discuss the therapeutic challenges.



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